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Table 2 Laboratory features in severe vs. non-severe hospitalized patients with COVID-19

From: Laboratory features of severe vs. non-severe COVID-19 patients in Asian populations: a systematic review and meta-analysis

Outcomes

Severe groups vs. non-severe groups

No

Pooled WMD (95% CI)

Heterogeneity (I2%, Pa)

Lymphocyte

22

− 0.43 (− 0.56, − 0.30)

90.1%, 0.000

Monocyte

10

− 0.06 (− 0.12, − 0.01)

71.8%, 0.000

Eosinophil

5

− 0.03 (− 0.05, − 0.00)

86.1%, 0.000

Hb

9

− 5.94 (− 8.23, − 3.64)

0.0%, 0.952

Platelet

17

− 27.97 (− 39.6, − 16.35)

55.8%, 0.003

Neutrophil

18

0.74 (0.16, 1.33)

74.6%, 0.000

WBC

21

0.55 (− 0.09, 1.19)

81.3%, 0.000

Albumin

12

− 4.20 (− 5.99, − 2.41)

73.9%, 0.000

ALT

15

6.65 (4.21, 9.09)

0.0%, 0.492

AST

14

11.91 (8.29, 15.53)

46.1%, 0.030

TBIL

9

0.08 (0.03, 0.14)

0.0%, 0.953

BUN

9

2.34 (0.66, 4.03)

39.3%, 0.106

Cr

14

0.08 (0.03, 0.12)

0.0%, 0.930

Creatine kinase

14

− 3.01 (− 12.91, 6.90)

51.7%, 0.013

Troponin I

5

0.27 (− 0.14, 0.67)

77.3%, 0.001

Myoglobin

3

8.11 (− 6.10, 22.33)

73.2%, 0.024

ESR

9

27.67 (22.94, 32.40)

22.3%, 0.245

CRP

18

36.61 (24.40, 48.82)

91.9%, 0.000

Lactate dehydrogenase

11

102.15 (72.76, 131.53)

50.3%, 0.028

Procalcitonin

12

0.03 (0.00, 0.06)

41.1%, 0.067

IL-6

6

0.54 (− 0.37, 1.45)

95.5%, 0.000

Sodium

9

− 1.95 (− 2.87, − 1.03)

75.5%, 0.000

Potassium

9

− 0.07 (− 0.18, 0.04)

34.3%, 0.144

Fibrinogen

4

0.8 (0.32, 1.28)

82.2%, 0.001

Protrombine

8

0.63 (0.27, 0.99)

69.2%, 0.002

D-dimer

12

0.18 (0.10, 0.27)

99.3%, 0.000

Glucose level

4

12.43 (1.95, 22.91)

0.0%, 0.433

Neutrophil‐to‐Lymphocyte ratio

18

0.23 (0.08, 0.37)

14.6%, 0.279

Lymphocyte-to-C-reactive protein ratio

18

− 8.12 (− 10.05, − 6.18)

98.6%, 0.000

Leukocyte-to-C-reactive protein ratio

17

− 1.47 (− 2.13, − 0.80)

94.6%, 0.000

Leukocyte-to-IL-6 ratio

5

− 0.99 (− 1.98, − 0.00)

93.6%, 0.000

  1. HB, hemoglobin; WBC, white blood cell; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TBIL, total bilirubin; BUN, blood urea nitrogen; Cr, Creatine; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; IL-6, interleukin 6