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Table 2 Laboratory features in severe vs. non-severe hospitalized patients with COVID-19

From: Laboratory features of severe vs. non-severe COVID-19 patients in Asian populations: a systematic review and meta-analysis

Outcomes Severe groups vs. non-severe groups
No Pooled WMD (95% CI) Heterogeneity (I2%, Pa)
Lymphocyte 22 − 0.43 (− 0.56, − 0.30) 90.1%, 0.000
Monocyte 10 − 0.06 (− 0.12, − 0.01) 71.8%, 0.000
Eosinophil 5 − 0.03 (− 0.05, − 0.00) 86.1%, 0.000
Hb 9 − 5.94 (− 8.23, − 3.64) 0.0%, 0.952
Platelet 17 − 27.97 (− 39.6, − 16.35) 55.8%, 0.003
Neutrophil 18 0.74 (0.16, 1.33) 74.6%, 0.000
WBC 21 0.55 (− 0.09, 1.19) 81.3%, 0.000
Albumin 12 − 4.20 (− 5.99, − 2.41) 73.9%, 0.000
ALT 15 6.65 (4.21, 9.09) 0.0%, 0.492
AST 14 11.91 (8.29, 15.53) 46.1%, 0.030
TBIL 9 0.08 (0.03, 0.14) 0.0%, 0.953
BUN 9 2.34 (0.66, 4.03) 39.3%, 0.106
Cr 14 0.08 (0.03, 0.12) 0.0%, 0.930
Creatine kinase 14 − 3.01 (− 12.91, 6.90) 51.7%, 0.013
Troponin I 5 0.27 (− 0.14, 0.67) 77.3%, 0.001
Myoglobin 3 8.11 (− 6.10, 22.33) 73.2%, 0.024
ESR 9 27.67 (22.94, 32.40) 22.3%, 0.245
CRP 18 36.61 (24.40, 48.82) 91.9%, 0.000
Lactate dehydrogenase 11 102.15 (72.76, 131.53) 50.3%, 0.028
Procalcitonin 12 0.03 (0.00, 0.06) 41.1%, 0.067
IL-6 6 0.54 (− 0.37, 1.45) 95.5%, 0.000
Sodium 9 − 1.95 (− 2.87, − 1.03) 75.5%, 0.000
Potassium 9 − 0.07 (− 0.18, 0.04) 34.3%, 0.144
Fibrinogen 4 0.8 (0.32, 1.28) 82.2%, 0.001
Protrombine 8 0.63 (0.27, 0.99) 69.2%, 0.002
D-dimer 12 0.18 (0.10, 0.27) 99.3%, 0.000
Glucose level 4 12.43 (1.95, 22.91) 0.0%, 0.433
Neutrophil‐to‐Lymphocyte ratio 18 0.23 (0.08, 0.37) 14.6%, 0.279
Lymphocyte-to-C-reactive protein ratio 18 − 8.12 (− 10.05, − 6.18) 98.6%, 0.000
Leukocyte-to-C-reactive protein ratio 17 − 1.47 (− 2.13, − 0.80) 94.6%, 0.000
Leukocyte-to-IL-6 ratio 5 − 0.99 (− 1.98, − 0.00) 93.6%, 0.000
  1. HB, hemoglobin; WBC, white blood cell; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TBIL, total bilirubin; BUN, blood urea nitrogen; Cr, Creatine; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; IL-6, interleukin 6