Table 2 Pooled prevalence of clinical features and laboratory findings of pregnant women with coronavirus infection in the present systematic review and meta-analysis
Clinical feature of patients with CoV infection | SARS-CoV-2 | MERS-CoV | SARS-CoV | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Study (n) | Reports (n) | Pregnancies (n) | Pooled % (95%-CI) | Study (n) | Reports (n) | Pregnancies (n) | Pooled % (95%-CI) | Study (n) | Reports (n) | Pregnancies (n) | Pooled % (95%-CI) | |
Fever | 19 | 575 | 870 | 66.1% [56.1–79.8] | 6 | 9 | 12 | 75% [30.2–88.9] | 7 | 32 | 33 | 96.9% [84.6–100] |
Cough | 18 | 458 | 869 | 52.7% [34.7–67.7] | 4 | 7 | 9 | 77.8% [40.1–97.5] | 6 | 21 | 26 | 80.8% [61.4–93.6] |
Fatigue | 8 | 192 | 634 | 30.3% [14.4–49.6] | 1 | 1 | 2 | 50% [1.2–99.2] | – | – | – | – |
Dyspnea | 7 | 49 | 303 | 16.2% [7.6–22.3] | 1 | 1 | 2 | 50% [1.4–99.6] | 1 | 9 | 10 | 90% [55.3–100] |
Myalgia | 5 | 61 | 293 | 20.8% [7.5–27.8] | 2 | 3 | 8 | 37.5 [9.3–76.2] | 2 | 16 | 22 | 72.7% [50.1–89.8] |
Shortness of Breath | 6 | 186 | 586 | 31.7% [18.2–41.5] | 1 | 1 | 2 | 50% [1.4–99.6] | 3 | 9 | 24 | 37.5% [19.2–59.6] |
Sore throat | 6 | 78 | 668 | 11.7% [5.1–29.1] | – | – | – | – | 2 | 5 | 22 | 22.7% [8.7–45.5] |
Chill | 3 | 44 | 480 | 9.2% [4.7–71.1] | – | – | – | – | 3 | 15 | 23 | 65.2% [43.1–84.8] |
Headache | 5 | 88 | 674 | 13.1% [8.5–33.2] | 1 | 1 | 2 | 50% [1.4–99.6] | 4 | 15 | 24 | 62.5% [41.3–81.9] |
Muscle pain | 3 | 67 | 628 | 10.7% [4.9–25.4] | – | – | – | – | 2 | 2 | 11 | 18.2% [3.2–35.9] |
Diarrhea | 9 | 41 | 753 | 5.4% [2.2–10.3] | 1 | 1 | 2 | 50% [1.4–99.6] | 2 | 3 | 22 | 13.6% [6.6–48.7] |
Abdominal pain | 2 | 5 | 64 | 7.8% [3.5–17.1] | 1 | 1 | 2 | 50% [1.4–99.6] | – | – | – | – |
Pneumonia | 21 | 368 | 517 | 71.2% [68.6–95.8] | 4 | 5 | 7 | 71.4% [29.5–96.2] | 5 | 8 | 9 | 88.9% [52.1–100] |
Laboratory finding | ||||||||||||
Leukocytosis | 6 | 27 | 95 | 28.4% [20.1–39.6] | – | – | – | – | 3 | 10 | 24 | 41.7% [22.1–63.2] |
Leukopenia | 6 | 43 | 95 | 45.3% [35.4–56.3] | – | – | – | – | 3 | 14 | 24 | 58.3% [37.2–78.3] |
Lymphocytosis | 12 | 8 | 70 | 11.4% [5.5–21.3] | – | – | – | – | 4 | 3 | 24 | 12.5% [3.2–32.8] |
Lymphocytopenia | 13 | 92 | 146 | 63% [55.7–71.4] | 1 | 1 | 1 | 100% [3.3–100] | 4 | 20 | 24 | 83.3% [63.1–95.5] |
ALT↑ | 3 | 9 | 48 | 18.8% [9.5–33.7] | 2 | 1 | 3 | 33.3% [1.6–91.3] | 2 | 2 | 8 | 25% [3.3–65.3] |
AST↑ | 3 | 8 | 48 | 16.7% [7.2–30.5] | 2 | 1 | 3 | 33.3% [1.6–91.3] | 2 | 2 | 8 | 25% [3.3–65.3] |
LDH↑ | 3 | 8 | 23 | 34.8% [16.2–57.9] | – | – | – | – | – | – | – | – |
C-reactive protein ↑ | 11 | 80 | 143 | 55.9% [47.4–64.2] | 1 | 1 | 1 | 100% [3.3–100] | 1 | 1 | 1 | 100% [3.3–100] |