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Table 2 Pooled prevalence of clinical features and laboratory findings of pregnant women with coronavirus infection in the present systematic review and meta-analysis

From: The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal–fetal transmission: a systematic review and meta-analysis

Clinical feature of patients with CoV infection

SARS-CoV-2

MERS-CoV

SARS-CoV

Study (n)

Reports (n)

Pregnancies (n)

Pooled % (95%-CI)

Study (n)

Reports (n)

Pregnancies (n)

Pooled % (95%-CI)

Study (n)

Reports (n)

Pregnancies (n)

Pooled % (95%-CI)

Fever

19

575

870

66.1% [56.1–79.8]

6

9

12

75% [30.2–88.9]

7

32

33

96.9% [84.6–100]

Cough

18

458

869

52.7% [34.7–67.7]

4

7

9

77.8% [40.1–97.5]

6

21

26

80.8% [61.4–93.6]

Fatigue

8

192

634

30.3% [14.4–49.6]

1

1

2

50% [1.2–99.2]

Dyspnea

7

49

303

16.2% [7.6–22.3]

1

1

2

50% [1.4–99.6]

1

9

10

90% [55.3–100]

Myalgia

5

61

293

20.8% [7.5–27.8]

2

3

8

37.5 [9.3–76.2]

2

16

22

72.7% [50.1–89.8]

Shortness of Breath

6

186

586

31.7% [18.2–41.5]

1

1

2

50% [1.4–99.6]

3

9

24

37.5% [19.2–59.6]

Sore throat

6

78

668

11.7% [5.1–29.1]

2

5

22

22.7% [8.7–45.5]

Chill

3

44

480

9.2% [4.7–71.1]

3

15

23

65.2% [43.1–84.8]

Headache

5

88

674

13.1% [8.5–33.2]

1

1

2

50% [1.4–99.6]

4

15

24

62.5% [41.3–81.9]

Muscle pain

3

67

628

10.7% [4.9–25.4]

2

2

11

18.2% [3.2–35.9]

Diarrhea

9

41

753

5.4% [2.2–10.3]

1

1

2

50% [1.4–99.6]

2

3

22

13.6% [6.6–48.7]

Abdominal pain

2

5

64

7.8% [3.5–17.1]

1

1

2

50% [1.4–99.6]

Pneumonia

21

368

517

71.2% [68.6–95.8]

4

5

7

71.4% [29.5–96.2]

5

8

9

88.9% [52.1–100]

Laboratory finding

 Leukocytosis

6

27

95

28.4% [20.1–39.6]

3

10

24

41.7% [22.1–63.2]

 Leukopenia

6

43

95

45.3% [35.4–56.3]

3

14

24

58.3% [37.2–78.3]

 Lymphocytosis

12

8

70

11.4% [5.5–21.3]

4

3

24

12.5% [3.2–32.8]

 Lymphocytopenia

13

92

146

63% [55.7–71.4]

1

1

1

100% [3.3–100]

4

20

24

83.3% [63.1–95.5]

 ALT↑

3

9

48

18.8% [9.5–33.7]

2

1

3

33.3% [1.6–91.3]

2

2

8

25% [3.3–65.3]

 AST↑

3

8

48

16.7% [7.2–30.5]

2

1

3

33.3% [1.6–91.3]

2

2

8

25% [3.3–65.3]

 LDH↑

3

8

23

34.8% [16.2–57.9]

 C-reactive protein ↑

11

80

143

55.9% [47.4–64.2]

1

1

1

100% [3.3–100]

1

1

1

100% [3.3–100]

  1. AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase