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Table 2 Pooled prevalence of clinical features and laboratory findings of pregnant women with coronavirus infection in the present systematic review and meta-analysis

From: The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal–fetal transmission: a systematic review and meta-analysis

Clinical feature of patients with CoV infection SARS-CoV-2 MERS-CoV SARS-CoV
Study (n) Reports (n) Pregnancies (n) Pooled % (95%-CI) Study (n) Reports (n) Pregnancies (n) Pooled % (95%-CI) Study (n) Reports (n) Pregnancies (n) Pooled % (95%-CI)
Fever 19 575 870 66.1% [56.1–79.8] 6 9 12 75% [30.2–88.9] 7 32 33 96.9% [84.6–100]
Cough 18 458 869 52.7% [34.7–67.7] 4 7 9 77.8% [40.1–97.5] 6 21 26 80.8% [61.4–93.6]
Fatigue 8 192 634 30.3% [14.4–49.6] 1 1 2 50% [1.2–99.2]
Dyspnea 7 49 303 16.2% [7.6–22.3] 1 1 2 50% [1.4–99.6] 1 9 10 90% [55.3–100]
Myalgia 5 61 293 20.8% [7.5–27.8] 2 3 8 37.5 [9.3–76.2] 2 16 22 72.7% [50.1–89.8]
Shortness of Breath 6 186 586 31.7% [18.2–41.5] 1 1 2 50% [1.4–99.6] 3 9 24 37.5% [19.2–59.6]
Sore throat 6 78 668 11.7% [5.1–29.1] 2 5 22 22.7% [8.7–45.5]
Chill 3 44 480 9.2% [4.7–71.1] 3 15 23 65.2% [43.1–84.8]
Headache 5 88 674 13.1% [8.5–33.2] 1 1 2 50% [1.4–99.6] 4 15 24 62.5% [41.3–81.9]
Muscle pain 3 67 628 10.7% [4.9–25.4] 2 2 11 18.2% [3.2–35.9]
Diarrhea 9 41 753 5.4% [2.2–10.3] 1 1 2 50% [1.4–99.6] 2 3 22 13.6% [6.6–48.7]
Abdominal pain 2 5 64 7.8% [3.5–17.1] 1 1 2 50% [1.4–99.6]
Pneumonia 21 368 517 71.2% [68.6–95.8] 4 5 7 71.4% [29.5–96.2] 5 8 9 88.9% [52.1–100]
Laboratory finding
 Leukocytosis 6 27 95 28.4% [20.1–39.6] 3 10 24 41.7% [22.1–63.2]
 Leukopenia 6 43 95 45.3% [35.4–56.3] 3 14 24 58.3% [37.2–78.3]
 Lymphocytosis 12 8 70 11.4% [5.5–21.3] 4 3 24 12.5% [3.2–32.8]
 Lymphocytopenia 13 92 146 63% [55.7–71.4] 1 1 1 100% [3.3–100] 4 20 24 83.3% [63.1–95.5]
 ALT↑ 3 9 48 18.8% [9.5–33.7] 2 1 3 33.3% [1.6–91.3] 2 2 8 25% [3.3–65.3]
 AST↑ 3 8 48 16.7% [7.2–30.5] 2 1 3 33.3% [1.6–91.3] 2 2 8 25% [3.3–65.3]
 LDH↑ 3 8 23 34.8% [16.2–57.9]
 C-reactive protein ↑ 11 80 143 55.9% [47.4–64.2] 1 1 1 100% [3.3–100] 1 1 1 100% [3.3–100]
  1. AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase
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