Fig. 1

The expression of miR-381 was decreased in pediatric AML patients. a Compared with the healthy control group, the expression level of miR-381 in pediatric AML bone marrow was significantly reduced. b Compared with the healthy control, the level of miR-381 in the serum of pediatric AML was significantly reduced. c The serum level of miR-381 in pediatric patients was positively correlated with the level of miR-381 in bone marrow (r = 0.7149). d Compared with normal human bone marrow stromal cells HS-5, the level of miR-381 in AML cells was significantly reduced. *** P < 0.001, compared with Healthy control