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Table 2 Characteristics of patients with 1 comorbidity or ≥ 2 comorbidities

From: Development of a quantitative segmentation model to assess the effect of comorbidity on patients with COVID-19

Variables

Without comorbidity (n = 242)

1 comorbidity (n = 38)

 ≥ 2 comorbidities (n = 14)

P1 value

P2 value

Gender

   

0.126

0.734

 Male

127 (52.5%)

13 (34.2%)

6 (42.9%)

  

 Female

115 (47.5%)

25 (65.8%)

8 (57.1%)

  

Age (years)

44.00 (32.00–53.00)

53.00 (47.00–61.00)

60.00 (52.00–67.00)

0.000

0.000

Incubation period (days)

3.00 (2.00–7.00)

6.00 (4.00–7.00)

8.00 (3.00–13.00)

0.029

0.041

Symptoms

     

 Fever

223 (92.2%)

38 (100%)

14 (100%)

0.149

0.572

 Dyspnea

129 (53.3%)

29 (76.3%)

12 (85.7%)

0.008

0.065

 More than one symptom

178 (73.6%)

35 (92.1%)

12 (85.7%)

0.479

0.486

CRP abnormal

   

0.021

0.072

 Yes

130 (53.7%)

28 (73.7%)

11 (78.6%)

  

 No

112 (46.3%)

10 (26.3%)

3 (21.4%)

  

WBC abnormal

   

0.138

0.064

 Yes

45 (18.6%)

11 (28.9%)

6 (42.9%)

  

 No

197 (81.4%)

27 (71.1%)

8 (57.1%)

  

LY count (× 109/L)

0.72 (0.51–1.12)

0.64 (0.39–0.94)

0.45 (0.27–0.89)

0.043

0.036

Severity status

   

0.000

0.000

 Yes

16 (6.6%)

14 (36.8%)

8 (57.1%)

  

 No

226 (93.4%)

22 (42.3%)

6 (42.9%)

  

Quantitative CT analysis

     

 LUV (cm3)

3709.28 (2939.74–4538.04)

3885.28 (2846.22–4916.78)

4170.63 (3129.45–4697.75)

0.606

0.252

 LEV (cm3)

127.82 (50.50–265.91)

235.87 (85.14–629.24)

237.17 (161.81–837.53)

0.001

0.009

 LEV/LUV

0.04 (0.01–0.08)

0.07 (0.02–0.15)

0.09 (0.04–0.27)

0.001

0.017

 COV (cm3)

40.45 (11.82–96.27)

97.89 (23.65–200.86)

94.86 (24.80–289.90)

0.001

0.022

 COV/LUV

0.01 (0.00–0.03)

0.03 (0.01–0.06)

0.04 (0.01–0.11)

0.001

0.046

 GGOV (cm3)

74.71 (31.08–150.72)

135.80 (49.43–281.20)

197.58 (66.95–377.93)

0.003

0.006

 GGOV /LUV

0.02 (0.01–0.04)

0.03 (0.02–0.10)

0.05 (0.02–0.15)

0.003

0.013

 LEN

19.00 (10.00–37.25)

31.00 (20.00–46.00)

30.00 (23.00–32.00)

0.001

0.202

  1. CRP: C reactive protein; WBC: white blood cell count; LY: lymphocyte; LUV: the volume of the whole lung; LEV: the volume of lesion; COV: the volume of consolidation; GGOV: the volume of GGO; LEN: the number of lesions
  2. P1 value: 1 comorbidity vs. without comorbidity; P2 value: ≥ 2 comorbidities vs. without comorbidity; P values written in italics indicate a significant difference
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European Journal of Medical Research

ISSN: 2047-783X

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