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Table 3 Characteristics of patients with different comorbidities

From: Development of a quantitative segmentation model to assess the effect of comorbidity on patients with COVID-19

Variables

Without comorbidity (n = 242)

Hypertension (n = 22)

Diabetes mellitus (n = 7)

Hepatitis B infection (n = 8)

P1 value

P2 value

P3 value

Gender

    

0.552

0.544

0.111

 Male

127 (52.5%)

13 (59.1%)

5 (71.4%)

7 (87.5%)

   

 Female

115 (47.5%)

9 (40.9%)

2 (28.6%)

1 (12.5%)

   

Age (years)

44.00 (32.00–53.00)

56.00 (48.50–62.25)

51.00 (43.00–69.00)

46.00 (43.00–52.00)

0.000

0.055

0.315

Incubation period (days)

3.00 (2.00–7.00)

6.50 (4.00–7.25)

6.00 (5.00–7.00)

4.00 (2.25–6.50)

0.076

0.208

0.835

Symptoms

       

 Fever

223 (92.2%)

22 (100%)

7 (100%)

8 (100%)

0.351

1.000

1.000

 Dyspnea

129 (53.3%)

19 (86.4%)

6 (85.7%)

4 (50.0%)

0.003

0.190

1.000

 More than one symptom

178 (73.6%)

21 (95.5%)

6 (85.7%)

6 (75.0%)

0.022

0.775

1.000

CRP abnormal

    

0.003

1.000

0.586

 Yes

130 (53.7%)

19 (86.4%)

4 (57.1%)

3 (37.5%)

   

 No

112 (46.3%)

3 (13.6%)

3 (42.9%)

5 (62.5%)

   

WBC abnormal

    

0.773

0.041

0.379

 Yes

45 (18.6%)

3 (13.6%)

4 (57.1%)

3 (37.5%)

   

 No

197 (81.4%)

19 (86.4%)

3 (42.9%)

5 (62.5%)

   

LY count (× 109/L)

0.72 (0.51–1.12)

0.60 (0.31–0.89)

0.69 (0.56–1.10)

0.56 (0.35–0.94)

0.044

0.977

0.039

Severity status

    

0.000

0.000

0.010

 Yes

16 (6.6%)

7 (31.8%)

3 (42.9%)

3 (37.5%)

   

 No

226 (93.4%)

15 (68.2%)

4 (57.1%)

5 (62.5%)

   

Pleural effusion

    

1.000

0.859

0.935

 Yes

13 (5.4%)

1 (4.5%)

1 (14.3%)

1 (12.5%)

   

 No

229 (94.6%)

21 (95.5%)

6 (85.7%)

7 (87.5%)

   

Quantitative CT analysis

       

 LUV (cm3)

3709.28 (2939.74–4538.04)

3279.78 (2647.81–4775.08)

4289.78 (3043.78–5644.50)

4457.41 (2895.61–5104.92)

0.545

0.400

0.393

 LEV (cm3)

127.82 (50.50–265.91)

192.55 (68.09–581.92)

570.00 (206.43–1365.34)

187.85 (76.33–361.09)

0.036

0.001

0.315

 LEV/LUV

0.04 (0.01–0.08)

0.05 (0.02–0.15)

0.17 (0.05–0.26)

0.04 (0.02–0.09)

0.033

0.001

0.429

 COV (cm3)

40.45 (11.82–96.27)

74.24 (21.58–212.75)

178.87 (119.98–605.27)

67.43 (21.00–168.81)

0.039

0.001

0.345

 COV/LUV

0.01 (0.00–0.03)

0.02 (0.01–0.06)

0.04 (0.03–0.11)

0.02 (0.00–0.05)

0.045

0.001

0.390

 GGOV (cm3)

74.71 (31.08–150.72)

104.19 (46.51–212.08)

369.13 (66.95–765.53)

82.82 (48.20–169.62)

0.075

0.004

0.471

 GGOV/LUV

0.02 (0.01–0.04)

0.03 (0.02–0.08)

0.10 (0.02–0.15)

0.02 (0.01–0.04)

0.047

0.003

0.590

 LEN

19.00 (10.00–37.25)

37.00 (20.00–46.25)

37.00 (22.00–46.00)

24.50 (16.75–45.25)

0.004

0.068

0.190

  1. CRP: C reactive protein; WBC: white blood cell count; LY: lymphocyte; LUV: the volume of the whole lung; LEV: the volume of lesion; COV: the volume of consolidation; GGOV: the volume of GGO; LEN: the number of lesions
  2. P1 value: hypertension vs. without comorbidity; P2 value: diabetes mellitus vs. without comorbidity; P3 value: hepatitis B infection vs. without comorbidity; P values written in italics indicate a significant difference
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European Journal of Medical Research

ISSN: 2047-783X

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