Table 1 Baseline characteristics and plasma drug concentrations in pregnant women with pregnancy-associated primary toxoplasmosis and non-pregnant females with acute ocular toxoplasmosis, both assayed in the advisory laboratory using liquid chromatography–mass spectrometry (LC–MS)

Age

 N

17

89

p = 0.024^a

 Mean ± SD [95% CI]

26.1 ± 5.3 [23.6; 28.5]

29.6 ± 6.0 [28.4; 30.9]

 Min–max

17–35

18.8–43.8

 Median

27

29.9

 Percentiles (25th; 75th)

21; 29

24.2; 33.6

PY (µg/l)

 N

17

89

p = 0.006^b

 Mean ± SD

1550 ± 1411

838 ± 434

 Min–max

29–6160

29–2550

 Median [95% CI]^d

1230 [780; 1890]

810 [745; 917]

 Percentiles (25th; 75th)

780; 1980

622; 1001

SA (mg/l)^c

 N

17

89

p = 0.015^b

 Mean ± SD

69.1 ± 44.2

44.5 ± 25.9

 Min–max

9.0–166.0

9.0–137.0

 Median [95% CI]^d

70.4 [52.4; 89]

46.2 [39.9; 54.4]

 Percentiles (25th; 75th)

52.4; 89.0

21.8; 62.5