Fig. 4From: Dose- and time-dependent effects of hyaluronidase on structural cells and the extracellular matrix of the skinInjection of low-dose HYAL (a) degrades HA in the extracellular matrix of the skin (b). HYAL and breakdown fragments of HA might be involved in induction of HA synthases resulting in accumulation of HA in the skin (c)Back to article page