Fig. 2
From: LncRNA NEAT1 promotes nucleus pulposus cell matrix degradation through regulating Nrf2/ARE axis
lncRNA NEAT1 was up-regulated in IVD tissue and NF-α/IL-1β-stimulated nucleus pulposus cells. a The lncRNA NEAT1 expression was increased upon elevated Pfirrmann grades. b The expression level of lncRNA NEAT1 was significantly increased in IVD tissues. c Expression of lncRNA NEAT1 in nucleus pulposus cells treated with different doses of TNF-α (0, 10, 25 and 50 ng/ml). d Expression of lncRNA NEAT1 in nucleus pulposus cells treated with TNF-α (50 ng/ml) at different time (0, 24, 48 and 72 h). e Expression of lncRNA NEAT1 in nucleus pulposus cells treated with different doses of IL-β (0, 5, 10 and 20 ng/ml). f Expression of lncRNA NEAT1 in nucleus pulposus cells treated with IL-β (20 ng/ml) at different time (0, 24, 48 and 72 h). *p < 0.05