TY - JOUR AU - Teuben, Michel Paul Johan AU - Hollman, Arne AU - Blokhuis, Taco AU - Pfeifer, Roman AU - Spijkerman, Roy AU - Teuber, Henrik AU - Pape, Hans-Christoph AU - Leenen, Luke Petrus Hendrikus PY - 2021 DA - 2021/03/15 TI - Splenectomy is associated with altered leukocyte kinetics after severe trauma JO - European Journal of Medical Research SP - 26 VL - 26 IS - 1 AB - Inadequate activation of the innate immune system after trauma can lead to severe complications such as Acute Respiratory Distress Syndrome and Multiple Organ Dysfunction Syndrome. The spleen is thought to modulate the cellular immune system. Furthermore, splenectomy is associated with improved outcome in severely injured trauma patients. We hypothesized that a splenectomy alters the cellular immune response in polytrauma. SN - 2047-783X UR - https://doi.org/10.1186/s40001-021-00497-8 DO - 10.1186/s40001-021-00497-8 ID - Teuben2021 ER -