EuroScore and IL-6 predict the course in ICU after cardiac surgery

Table 2 Investigation of possible predictors for mortality after cardiac surgery

Variable	Category	OR	95% CI	p value^h
Age^a	Linear	1.08	[1.03, 1.12]	0.001
Sex^b	Male	1	[1.00, 1.00]	0.03
	Female	1.46	[0.77, 2.79]	0.03
EF [%]^c	25–45	1	[1.00, 1.00]	0.0003
	46–64	0.19	[0.07, 0.57]
	65	0.3	[0.16, 0.58]
EuroScore^d	0–2	1	[1.00, 1.00]	< 0.001
	3–5	2.05	[0.41, 10.17]
	> 6	13.25	[3.15, 55.81]
Creatinine [mg/dl]^e	< 1.2	1	[1.00, 1.00]	< 0.001
	1.2–2.1	5.6	[2.67, 11.76]
	> 2.1	13.09	[4.66, 36.81]
IL-6 [pg/ml]^f	Q1 (< 102)	1	[1.00, 1.00]	< 0.001
	Q2 (102–165)	1.51	[0.25, 9.09]
	Q3 (166–256)	2.01	[0.37, 11.02]
	Q4 (257–421)	2.03	[0.37, 11.11]
	Q5 (> 421)	12.6	[2.96, 53.55]
CPB [min]^g		2.3	1.66, 3.15	< 0.001

Logistic regression model investigating possible predictors for death (yes/no) after cardiac surgery. Only results from the univariable models are displayed
EF ejection fraction, CPB cardiopulmonary bypass, OR odds ratio, CI confidence interval
^aAge is analysed as linear variable
^bThe reference category are male
^cEF displayed in quintiles (resulting in 3 groups), reference category are values 45
^dEuroScore is analysed in three groups according to guidelines: mild/moderate/severe risk. The reference category is the lowest score
^eCreatinine is displayed in three groups. The reference category are lowest values
^fIL-6 is displayed in quintiles. The reference category is the first quintile
^gCPB. Due to the low (missing) number of deaths in the lower quintiles, overall OR is displayed
^hp value: from likelihood ratio test

ISSN: 2047-783X