From: EuroScore and IL-6 predict the course in ICU after cardiac surgery
Variable | Category | Univariable model | Multivariable model | ||||
---|---|---|---|---|---|---|---|
OR | 95% CI | p valuej | OR | 95% CI | p valuej | ||
Age [years]a | Linear | 1.03 | [1.02, 1.04] | < 0.001 | 1.01 | [1.00, 1.02] | 0.004 |
Sexb | Male | 1 | [1.00, 1.00] | 0.066 | 1 | [1.00, 1.00] | 0.15 |
Female | 1.16 | [0.99, 1.36] | 1.15 | [0.95, 1.38] | |||
EF [%]c | ≤ 45 | 1 | [1.00, 1.00] | 0.015 | 1 | [1.00, 1.00] | 0.004 |
46–64 | 0.76 | [0.61, 0.95] | 1.02 | [0.80, 1.29] | |||
≥ 65 | 0.59 | [0.49, 0.71] | 0.77 | [0.62, 0.95] | |||
EuroScored | 0–2 | 1 | [1.00, 1.00] | < 0.001 | 1 | [1.00, 1.00] | < 0.001 |
3–5 | 1.56 | [1.29, 1.88] | 1.29 | [1.03, 1.62] | |||
> 6 | 3.05 | [2.50, 3.74] | 2.07 | [1.58, 2.72] | |||
Creatinine [mg/dl]e | < 1.2 | 1 | [1.00, 1.00] | < 0.001 | 1 | [1.00, 1.00] | < 0.001 |
1.2–2.1 | 1.73 | [1.48, 2.04] | 1.54 | [1.29, 1.83] | |||
> 2.1 | 2.99 | [1.93, 4.63] | 1.9 | [1.18, 3.05] | |||
IL-6 [pg/ml]f | Q1 (< 102) | 1 | [1.00, 1.00] | 0.009 | 1 | [1.00, 1.00] | 0.003 |
Q2 (102–165) | 1.01 | [0.80, 1.427] | 1.16 | [0.91, 1.49] | |||
Q3 (166–256) | 1.16 | [0.92, 1.46] | 1.35 | [1.05, 1.73] | |||
Q4 (257–421) | 1.11 | [0.88, 1.40] | 1.39 | [1.07, 1.80] | |||
Q5 (> 421) | 1.45 | [1.16, 1.83] | 1.79 | [1.38, 2.32] | |||
CPB [min]g | Q1 (< 72) | 1 | [1.00, 1.00] | < 0.001 | 1 | [1.00, 1.00] | < 0.001 |
Q2 (72–85) | 1 | [0.80, 1.27] | 0.97 | [0.76, 1.24] | |||
Q3 (86–100) | 1.04 | [0.82, 1.31] | 0.97 | [0.75, 1.24] | |||
Q4 (101–124) | 1.16 | [0.92, 1.46] | 1.09 | [0.85, 1.40] | |||
Q5 (> 124) | 1.83 | [1.45, 2.30] | 1.66 | [1.27, 2.16] | |||
Operationh | CABG | 1 | [1.00, 1.00] | < 0.001 | 1 | [1.00, 1.00] | 0.53 |
AV | 0.99 | [0.83, 1.018] | 1.01 | [0.83, 1.24] | |||
CABG + AV | 1.43 | [1.13, 1.80] | 1.08 | [0.82, 1.43] | |||
MV | 1.13 | [0.87, 1.47] | 1.08 | [0.80, 1.45] | |||
MV + TV | 3.26 | [1.78, 5.97] | 1.78 | [0.91, 3.51] |