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Table 2 Treatment outcomes and adverse reactions among patients with M/XDR-TB

From: Treatment outcomes of patients with multidrug and extensively drug-resistant tuberculosis in Zhejiang, China

Treatment outcome

Total MDR-TB

XDR-TB

Non-XDR-TB

χ2

P

(N = 262), n (%)

(N = 18), n (%)

(N = 244), n (%)

Treatment success (Cure, TC)

145(55.34)

6(33.33)

139(56.97)

3.789

0.052

Cure

140(53.44)

6(33.33)

134(54.92)

2.331

0.126

Completed

5(1.91)

0(0.00)

5(2.05)

0.078

0.779

Failure

62(23.66)

9(50.00)

53(21.72)

7.420

0.006

Death

27(10.31)

2(11.11)

25(10.25)

0.081

0.775

Default

16(6.11)

0(0.00)

16(6.56)

0.373

0.541

Transfer out

12(4.58)

1(5.56)

11(4.51)

0.143

0.704

Adverse drug reactions

122 (46.55)

7(38.89)

115(47.13)

0.458

0.499

GI upseta

98(37.40)

5(27.78)

93(38.11)

2.313

0.315

Hepatotoxicity

36(13.74)

1(5.56)

35(14.34)

5.522

0.063

Allergic reaction

17(6.49)

0(0.00)

17(6.97)

6.281

0.043

Neurologic abnormalities

5(1.91)

0(0.00)

5(2.05)

5.434

0.066

Mental disorder

2(0.76)

0(0.00)

2(0.82)

5.296

0.071

Hematologic abnormalities

2(0.76)

0(0.00)

2(0.82)

5.296

0.071

Electrolyte disturbances

3(1.15)

0(0.00)

3(1.23)

5.429

0.068

Renal toxicity

5(1.91)

0(0.00)

5(2.05)

5.434

0.066

Arthralgia or Courbature

25(9.54)

2(11.11)

23(9.43)

3.975

0.137

Hypothyroidism

10(3.82)

1(5.56)

9(3.69)

5.049

0.080

  1. aGI gastrointestinal