Skip to main content

Table 2 Treatment outcomes and adverse reactions among patients with M/XDR-TB

From: Treatment outcomes of patients with multidrug and extensively drug-resistant tuberculosis in Zhejiang, China

Treatment outcome Total MDR-TB XDR-TB Non-XDR-TB χ2 P
(N = 262), n (%) (N = 18), n (%) (N = 244), n (%)
Treatment success (Cure, TC) 145(55.34) 6(33.33) 139(56.97) 3.789 0.052
Cure 140(53.44) 6(33.33) 134(54.92) 2.331 0.126
Completed 5(1.91) 0(0.00) 5(2.05) 0.078 0.779
Failure 62(23.66) 9(50.00) 53(21.72) 7.420 0.006
Death 27(10.31) 2(11.11) 25(10.25) 0.081 0.775
Default 16(6.11) 0(0.00) 16(6.56) 0.373 0.541
Transfer out 12(4.58) 1(5.56) 11(4.51) 0.143 0.704
Adverse drug reactions 122 (46.55) 7(38.89) 115(47.13) 0.458 0.499
GI upseta 98(37.40) 5(27.78) 93(38.11) 2.313 0.315
Hepatotoxicity 36(13.74) 1(5.56) 35(14.34) 5.522 0.063
Allergic reaction 17(6.49) 0(0.00) 17(6.97) 6.281 0.043
Neurologic abnormalities 5(1.91) 0(0.00) 5(2.05) 5.434 0.066
Mental disorder 2(0.76) 0(0.00) 2(0.82) 5.296 0.071
Hematologic abnormalities 2(0.76) 0(0.00) 2(0.82) 5.296 0.071
Electrolyte disturbances 3(1.15) 0(0.00) 3(1.23) 5.429 0.068
Renal toxicity 5(1.91) 0(0.00) 5(2.05) 5.434 0.066
Arthralgia or Courbature 25(9.54) 2(11.11) 23(9.43) 3.975 0.137
Hypothyroidism 10(3.82) 1(5.56) 9(3.69) 5.049 0.080
  1. aGI gastrointestinal