Table 1 Baseline and intra-operative characteristics in patients with and without surgery-related loss of muscle quantity or quality
From: Risk factors for surgery-related muscle quantity and muscle quality loss and their impact on outcome
Factors | Total n = 128 (100%) | Muscle quantity loss n = 67 (52%) | No muscle quantity loss n = 61 (48%) | P-value | Muscle quality loss n = 83 (65%) | No muscle quality loss n = 45 (35%) | P-value |
|---|---|---|---|---|---|---|---|
Age, mean (SD), years | 65.5 (8.7) | 65.4 (7.7) | 65.6 (9.6) | 0.896 | 66.9 (7.8) | 62.7 (9.6) | 0.008 |
Sex, male | 89 (69.5%) | 50 (74.6%) | 39 (63.9%) | 0.249 | 62 (74.7%) | 27 (60.0%) | 0.085 |
BMI, mean (SD), kg/m2 | 25.6 (3.1) | 25.9 (3.0) | 25.5 (3.2) | 0.473 | 25.8 (3.1) | 25.5 (3.1) | 0.677 |
CEAa, median (IQR), μg/L | 6.3 (2.8–22.3) | 5.7 (2.4–19.0) | 8.0 (3.2–33) | 0.146 | 6.5 (2.9–35.0) | 5.6 (2.6–15.0) | 0.322 |
ASA score | |||||||
 I | 14 (10.9%) | 7 (10.4%) | 7 (11.5%) | 0.580 | 6 (7.2%) | 8 (17.8%) | 0.184 |
 II | 107 (83.6%) | 55 (82.1%) | 52 (85.2%) |  | 72 (86.7%) | 35 (77.8%) |  |
 III | 7 (5.5%) | 5 (7.5%) | 2 (3.3%) |  | 5 (6.0%) | 2 (4.4%) |  |
Comorbidities | |||||||
 Diabetes | 7 (5.5%) | 5 (7.5%) | 2 (3.3%) | 0.298 | 5 (6%) | 2 (4.4%) | 0.707 |
 Chronic obstructive pulmonary disease | 6 (4.7%) | 5 (7.5%) | 1 (1.6%) | 0.120 | 4 (4.8%) | 2 (4.4%) | 0.924 |
Charlson Comorbidity Index | |||||||
 0 | 103 (80.5%) | 53 (79.1%) | 50 (82%) | 0.786 | 66 (79.5%) | 37 (82.2%) | 0.867 |
 I | 19 (14.8%) | 10 (14.9%) | 9 (14.8%) |  | 13 (15.7%) | 6 (13.3%) |  |
 II | 5 (3.9%) | 3 (4.5%) | 2 (3.2%) |  | 3 (3.6%) | 2 (4.4%) |  |
 III | 1 (0.8%) | 1 (1.5%) | 0 (0.0%) |  | 1 (1.2%) | 0 (0.0%) |  |
CT scan | |||||||
 Time-frame pre-scan and OK, mean (SD), days | 28.2 (9.6) | 28.4 (9.9) | 27.9 (9.2) | 0.755 | 27.1 (9.5) | 30.1 (9.5) | 0.091 |
 Time-frame OK and post-scan, mean (SD), days | 7.1 (3.0) | 7.4 (3.4) | 6.6 (2.5) | 0.130 | 6.7 (2.7) | 7.6 (3.5) | 0.175 |
Operation type | |||||||
 Laparoscopic/open | 15 (11,7%)/113 (88,3%) | 6 (9.0%)/61 (91%) | 9 (14.8%)/52 (85.2%) | 0.308 | 4 (4,8%)/79 (95.2%) | 11 (24,4%)/34 (75,6%) | 0.001 |
 Minor/major | 74 (57.8%)/54 (42.2%) | 37 (55.2%)/30 (44.8%) | 37 (60.7%)/24 (39.3%) | 0.534 | 47 (56.6%)/36 (43.3%) | 27 (60.0%)/18 (40%) | 0.712 |
 Resection/resection + RFA | 104 (81.3%)/24 (18.8%) | 49 (73.1%)/18 (26.9%) | 55 (90.2%)/6 (9.8%) | 0.014 | 65 (78.3%)/18 (21.7%) | 39 (86.7%)/6 (13.3%) | 0.248 |
Operation parameters | |||||||
 Blood loss, median (IQR), mL | 400 (200–750) | 400 (187–700) | 400 (200–800) | 0.728 | 500 (200–763) | 300 (100–625) | 0.062 |
 Operation time, mean (SD), min | 134.2 (61.6) | 130.2 (58.9) | 138.8 (64.6) | 0.434 | 142.7 (65) | 118.1 (51.1) | 0.035 |