Characteristic | All (n = 1014) | Non-ICU (n = 809) | ICU (n = 205) | p-value |
---|---|---|---|---|
Demographics | ||||
 Age, mean ± SD, years | 47.2 ± 19.3 (1–104) | 45.3 ± 19.3 (1–104) | 52.9 ± 17.3 (5–95) |  ≤ 0.0005 |
Distribution | ||||
 0–10 years | 28 (2.8%) | 20 (2.5%) | 8 (3.9%) |  ≤ 0.0005 |
 11–20 years | 37 (3.6%) | 33 (4.2%) | 4 (1.9%) |  |
 21–30 years | 126 (12.5%) | 110 (13.6%) | 16 (7.8%) |  |
 31–40 years | 214 (21.1%) | 195 (24.1%) | 19 (9.3%) |  |
 41–50 years | 164 (16.2%) | 137 (16.9%) | 27 (13.2%) |  |
 51–60 years | 186 (18.3%) | 155 (19.2%) | 31 (15.1%) |  |
 61–70 years | 144 (14.2%) | 108 (13.3%) | 36 (17.6%) |  |
 71–80 years | 65 (6.4%) | 32 (3.9%) | 33 (16.1%) |  |
 81–90 years | 37 (3.6%) | 10 (1.2%) | 27 (13.2%) |  |
  ≥ 90 years | 13 (1.3%) | 9 (1.1%) | 4 (1.9%) |  |
Gender | ||||
 Male | 582 (57.4%) | 466 (57.6%) | 116 (56.5%) | 0.858 |
 Female gender | 432 (42.6%) | 343 (42.4%) | 89 (43.5%) |  |
Nationality | ||||
 Saudi | 900 (88.8%) | 721 (89.1%) | 179 (87.3%) | 0.886 |
 Non-Saudi | 114 (11.2%) | 88 (10.9%) | 26 (12.7%) |  |
Occupation | ||||
 Healthcare worker | 21 (2.1%) | 16 (2%) | 5 (2.4%) | 0.755 |
 Non-healthcare worker | 993 (97.9%) | 793 (98%) | 200 (97.6%) |  |
Smoking status | ||||
 Not a smoker | 920 (90.7%) | 786 (97.2%) | 134 (65.4%) | 0.223 |
 Past smoker | 35 (3.4%) | 6 (0.7%) | 29 (14.1%) |  |
 Current smoker | 59 (5.9%) | 17 (2.1%) | 42 (20.5%) |  |
Hospital | ||||
 King Fahad Hofuf Hospital | 300 (29.6%) | 249 (30.8%) | 51 (24.9%) |  ≤ 0.0005 |
 Aljabr Eye and ENT Hospital | 218 (21.5%) | 174 (21.5%) | 44 (21.5%) |  |
 Alomran General Hospital | 200 (19.7%) | 150 (18.5%) | 50 (24.4%) |  |
 King Faisal General Hospital | 163 (16.1%) | 152 (18.8%) | 11 (5.4%) |  |
 Maternity and Children Hospital | 71 (7%) | 55 (6.8%) | 16 (7.8%) |  |
 Prince Saud Bin Jalawi Hospital | 62 (6.1%) | 29 (3.6%) | 33 (16%) |  |
Educational level | ||||
 Illiterate | 146 (14.4%) | 61 (7.5%) | 85 (41.5%) | 0.06 |
 Primary to secondary | 529 (52.2%) | 449 (55.5%) | 80 (39%) |  |
 University | 172 (17%) | 153 (18.9%) | 19 (9.3%) |  |
 Unknown | 167 (16.4%) | 146 (18.1%) | 21 (10.2%) |  |
Exposure history | ||||
 Contact with positive confirmed case | 668 (65.9%) | 548 (67.7%) | 120 (58.5%) | 0.062 |
 Familiar/cluster infections | 180 (17.8%) | 149 (18.4%) | 31 (15.1%) |  |
 Hospital staff | 21 (2.1%) | 17 (2.1%) | 4 (1.9%) |  |
 From outside Saudi | 1 (0.1%) | 1 (0.1%) | 0 |  |
 Unknown | 144 (14.1%) | 94 (11.6%) | 50 (24.4%) |  |
Highest temperature (°C): | ||||
  < 37.3 | 467 (46.1%) | 414 (51.3%) | 53 (25.8%) |  ≤ 0.0005 |
 37.3–38.0 | 338 (33.3%) | 226 (27.9%) | 112 (54.7%) |  |
 38.01–39.0 | 147 (14.5%) | 116 (14.3%) | 31 (15.1%) |  |
  > 39.0 | 62 (6.1%) | 53 (6.5%) | 9 (4.4%) |  |
 Respiratory rate > 24 breaths per min | 312 (30.8%) | 168 (20.8%) | 144 (70.2%) |  ≤ 0.0005 |
Comorbidities | ||||
 Diabetes | 202 (19.9%) | 142 (17.5%) | 60 (29.3%) |  ≤ 0.0005 |
 Hypertension | 276 (27.2%) | 165 (20.4%) | 111 (54.1%) |  ≤ 0.0005 |
 Obesity (BMI ≥ 30 kg/m2) | 91 (9%) | 65 (8%) | 26 (12.7%) | 0.048 |
 Asthma | 26 (2.6%) | 15 (1.8%) | 11 (5.4%) | 0.179 |
 Coronary artery disease | 16 (1.6%) | 7 (0.9%) | 9 (4.4%) | 0.778 |
 Thalassemia | 3 (0.3%) | 0 | 3 (1.5%) | 0.222 |
 Chronic kidney disease | 5 (0.5%) | 0 | 5 (2.4%) | 0.592 |
 Liver disease | 1 (0.1%) | 0 | 1 (0.5%) | 0.778 |
 Cerebrovascular disease | 6 (0.6%) | 3 (0.4%) | 3 (1.5%) | 0.127 |
 Cancer | 5 (0.5%) | 1 (0.1%) | 4 (1.9%) | 0.691 |
 Cardiomyopathies | 3 (0.3%) | 1 (0.1%) | 2 (1%) | 0.395 |
 Heart failure | 2 (0.2%) | 0 | 2 (1%) | 0.605 |
 Ischemic heart disease | 12 (1.2%) | 3 (0.4%) | 9 (4.4%) | 0.520 |
 Sickle cell disease | 31 (3%) | 17 (2.1) | 14 (6.8%) | 0.039 |
 G6PD deficiency | 14 (1.4%) | 11 (1.3%) | 3 (1.5%) | 0.621 |
 Pregnant | 18 (1.8%) | 10 (1.2%) | 8 (3.9%) | 0.379 |
 Asymptomatic | 152 (15%) | 148 (18.3%) | 4 (1.9%) |  ≤ 0.0005 |
Symptoms | ||||
 Fever | 348 (34.3%) | 230 (28.4%) | 118 (57.6%) |  ≤ 0.0005 |
 Shortness of breath | 362 (35.7%) | 248 (30.6%) | 114 (55.6%) |  ≤ 0.0005 |
 Cough | 484 (47.7%) | 338 (41.8%) | 146 (71.2%) |  ≤ 0.0005 |
 Aches and pains | 43 (4.2%) | 24 (3%) | 19 (9.3%) | 0.139 |
 Loss of taste or smell | 54 (5.3%) | 38 (4.7%) | 16 (7.8%) | 0.562 |
 Nausea | 19 (1.9%) | 14 (1.7%) | 5 (2.4%) | 0.170 |
 Chest pain | 42 (4.1%) | 26 (3.2%) | 16 (7.8%) | 0.258 |
 Sore throat | 46 (4.5%) | 27 (3.3%) | 19 (9.3%) | 0.053 |
 Headache | 70 (6.9%) | 46 (5.7%) | 24 (11.7%) | 0.063 |
 Diarrhea | 70 (6.9%) | 62 (7.7%) | 8 (3.9%) | 0.077 |
 Fatigue | 74 (7.3%) | 42 (5.2%) | 32 (15.6%) | 0.011 |
 Myalgia | 68 (6.7%) | 44 (5.4%) | 24 (11.7%) | 0.153 |
 Abdominal pain | 25 (2.5%) | 19 (2.3%) | 6 (2.9%) | 0.102 |
 Vomiting | 28 (2.8%) | 24 (3%) | 4 (1.9%) | 0.013 |
 Anorexia | 39 (3.8%) | 27 (3.3%) | 12 (5.8%) | 0.399 |
 Rash | 12 (1.1%) | 9 (1.1%) | 3 (1.5%) | 0.470 |
 Dizziness | 18 (1.8%) | 5 (0.6%) | 13 (6.3%) | 0.024 |
Time from exposure to the onset of illness (days) | 5.39 ± 3.8 (1–15) | 5.98 ± 3.96 (1–14) | 4.49 ± 3.5 (2–15) | 0.041 |
Time from illness onset to first hospital admission (days) | 5.99 ± 3.9 (1–30) | 5.97 ± 3.7 (1–22) | 6.04 ± 4.45 (1–30) | 0.646 |