Fig. 1

The Prometheus paradigm. The societies for orthopaedics and traumatology need to identify and define problems of the patient suffering from orthopaedic or (post)traumatic problems, which are so far diagnostically and therapeutically not satisfactorily resolved. Then, based on the “Prometheus” principle, a highly intelligent and innovative idea, evolved in the interdisciplinary discourse, may lead to a perfectly designed basic science study to reveal the underlying mechanisms. This can be realized, e.g. by a translational study with appropriate in vitro or in vivo (animal) modelling. The gained knowledge can then be translated back to the clinic and subsequently be evaluated for the final benefit of the patient