Fig. 4

Cangrelor ameliorates the inflammatory response through GPR17. A MPO concentration in lung tissue. B Serum concentrations of TNF-α, IL-1β, and IL-6 (C) mRNA level of GPR17. D Western blot of GPR17 in lung tissue. Results are presented as means ± SD (n = 8). ^**p < 0.01, ^***p < 0.001 compared to the sham control; ^##p < 0.01, ^###p < 0.001 compared to CLP