Determination of parasitic burden in the brain tissue of infected mice in acute toxoplasmosis after treatment by fluconazole combined with sulfadiazine and pyrimethamine

Table 2 The parasite burden in different treatment groups by various doses of FLZ + SDZ/PYR

Groups	Days after challenge		P value
Groups	One day after the end of medication	Last day (before death)	P value
Untreated	–	11,804,800	P < 0.001
SDZ/PYR 40/1	5,152,800	2,965,200	P < 0.001
P value	P < 0.009
Untreated	–	11,804,800	P < 0.001
FLZ 10 + SDZ/PYR 40/1	1,324,400	1,052,000	P < 0.001
P value	P < 0.009
Untreated	–	11,804,800	P < 0.001
FLZ 20 + SDZ/PYR 40/1	1,101,600	762,000	P < 0.001
P value	P < 0.009

ISSN: 2047-783X