Fig. 1
From: Co-existence of Alport syndrome and C3 glomerulonephritis in a proband with family history
Family pedigree and Sanger sequencing chromatograms. a Pedigree structure of the family with Alport syndrome. Squares and circles denote males and females, respectively. Roman numbers indicate generations. Arrow indicates the proband (III:1). Family members carrying the heterozygous CFHR5 genetic variant (c.508G > A; Val170Met) are highlighted. Individuals II:4 and III:2 do not carry the Val170Met variant. b Sequence electropherogram shows a heterozygous CFHR5 c.508G > A (p.Val170Met) variation (arrow) in individual I:1, II:1, and III:1. c Sequence electropherogram shows the negative control