Table 2 Crude and adjusted odds ratios for the association of esophageal cancer and various risk factors
Variables | Cases | Control | ORC (95% CI) | ORadj (95% CI) | p value | ||
|---|---|---|---|---|---|---|---|
N = 105 | N = 105 | ||||||
Gender | 0.261 | ||||||
Female | 42 | (40.0%) | 56 | (53.3%) | 1.0 (reference) | 1.0 (reference) | |
Male | 63 | (60.0%) | 49 | (46.7%) | 1.7 (0.98–2.96) | 1.3 (0.77–2.53) | |
Age (years) | 0.339 | ||||||
< 60 | 14 | (13.3%) | 35 | (33.4%) | 1.0 (reference) | 1.0 (reference) | |
≥ 60 | 91 | (86.7%) | 70 | (66.6%) | 1.8 (0.99–3.01) | 1.4 (0.71- 2.81) | |
Body mass index; BMI (kg/m2) | 0.912 | ||||||
< 23.00 | 49 | (46.7%) | 54 | (51.4%) | 1.00 (reference) | 1.00 (reference) | |
≥ 23.00 | 56 | (53.3%) | 51 | (48.6%) | 1.21 (0.71–2.08) | 1.03 (0.55–1.95) | |
Marital status | 0.810 | ||||||
Single | 9 | (8.6%) | 9 | (8.6%) | 1.00 (reference) | 1.00 (reference) | |
Married | 88 | (83.8%) | 89 | (84.8%) | 0.98 (0.37–2.61) | 0.01 (0.35–2.93) | |
Separated | 8 | (7.6%) | 7 | (6.7%) | 1.14 (0.28–4.21) | 1.11 (0.26–5.63) | |
Drinking status | 0.016 | ||||||
Non-drinker | 33 | (31.4%) | 64 | (61.0%) | 1.0 (reference) | 1.0 (reference) | |
Drinker | 72 | (68.6%) | 41 | (39.0%) | 3.4 (1.93–6.02) | 3.2 (1.25–8.62) | |
Smoking status | 0.015 | ||||||
Non-smoker | 45 | (48.2%) | 72 | (68.6%) | 1.0 (reference) | 1.0 (reference) | |
Smoker | 60 | (51.8%) | 33 | (31.4%) | 3.3 (1.86–5.77) | 3.5 (1.28–9.56) | |
Family history of cancer in first-degree relatives | 0.001 | ||||||
No | 27 | (25.7%) | 60 | (57.1%) | 1.0 (reference) | 1.0 (reference) | |
Yes | 78 | (74.3%) | 45 | (42.9%) | 3.8 (2.15–6.91) | 3.7 (1.69–8.12) | |
Personal history of gastro esophagus reflux diseases (GERD) | 0.008 | ||||||
No | 25 | (23.8%) | 65 | (61.9%) | 1.0 (reference) | 1.0 (reference) | |
Yes | 80 | (76.2%) | 40 | (38.1%) | 4.2 (2.86–9.44) | 2.8 (1.29–5.62) | |
Poor oral hygiene | < 0.001 | ||||||
No | 33 | (31.4%) | 55 | (52.4%) | 1.0 (reference) | 1.0 (reference) | |
Yes | 72 | (68.6%) | 50 | (47.6%) | 2.8 (1.36–4.21) | 3.0 (1.44–6.26) | |