Parameters | Dose group | Total (N = 33) | p-value | ||||
---|---|---|---|---|---|---|---|
240 mg (N = 6) | 480 mg (N = 6) | 960 mg (N = 6) | 1440 mg (N = 7) | Placebo (N = 8) | |||
Age (years) | 26.50 ± 5.75 | 27.67 ± 3.98 | 26.83 ± 1.83 | 26.14 ± 3.02 | 25.38 ± 4.72 | 26.42 ± 3.92 | 0.7707 |
Height (cm) | 173.40 ± 7.34 | 173.75 ± 4.38 | 172.03 ± 3.86 | 176.37 ± 3.90 | 174.56 ± 5.70 | 174.13 ± 5.08 | 0.6516 |
Weight (kg) | 74.50 ± 10.44 | 72.75 ± 6.99 | 65.63 ± 9.08 | 74.56 ± 6.43 | 69.11 ± 5.84 | 71.28 ± 8.04 | 0.1871 |
BMI (kg/m2) | 24.67 ± 1.87 | 24.05 ± 1.15 | 22.10 ± 2.15 | 23.94 ± 1.46 | 22.70 ± 1.95 | 23.46 ± 1.90 | 0.0777 |
IBW (kg) | 66.05 ± 6.60 | 66.40 ± 3.93 | 64.85 ± 3.47 | 68.73 ± 3.51 | 67.10 ± 5.13 | 66.72 ± 4.57 | 0.6516 |
Alcohol (n, %) | 3 (50.0) | 4 (66.7) | 1 (16.7) | 3 (42.9) | 6 (75.0) | 17 (51.5) | 0.2748 |
Smoking (n, %) | 4 (66.7) | 3 (50.0) | 3 (50.0) | 3 (42.9) | 2 (25.0) | 15 (45.5) | 0.6525 |