Fig. 3

Assessment of DEGs’ networks. Networks in the control and AMI groups are independent and separable according to the average clustering coefficients of DEGs (A). Number of clusters within DEGs’ networks progressively decline when thresholds increase from 0.1 to 0.9 (B). The AMI group has a lower slope decline. The gene networks of DEGs in the AMI group have more complex connection, compared to that in the control group (C). Networks are present under threshold 0.5 and 0.7. Darker line represents connections under threshold 0.7; lighter line represents connections under threshold 0.5. DEGs differential expression genes