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Table 2 Top six gene enrichment outputs of DCGs and hub gene clusters

From: NR4A3 and CCL20 clusters dominate the genetic networks in CD146+ blood cells during acute myocardial infarction in humans

Biological process

  

CCL20 cluster

NR4A3 cluster

DCGs

Immune response

Cellular response to corticotropin-releasing hormone stimulus

Response to organic substance

Immune system process

Positive regulation of leukocyte activation

Positive regulation of leukocyte activation

Response to organic substance

Response to organic substance

Immune response

Regulation of cytokine production

Cellular response to organic substance

Immune system process

Response to cytokine

Regulation of apoptotic process

Response to cytokine

Regulation of localization

Response to cytokine

Regulation of cytokine production

Reactome pathway

 Immune system

Signaling by interleukins

Immune system

 Innate immune system

RNA polymerase II transcription

Signaling by interleukins

 Signaling by interleukins

Generic transcription pathway

Interleukin-4 and interleukin-13 signaling

 Cytokine signaling in immune system

Cytokine signaling in immune system

Innate immune system

 Dectin-2 family

Gene expression (transcription)

Interleukin-1 signaling

 Neutrophil degranulation

MyD88 cascade initiated on plasma membrane

Dectin-2 family

  1. DCGs differential connectivity genes