Study ID | Main adverse reactions | Major adverse reactions leading to interruption of treatment |
---|---|---|
Azuma 2005 | Photosensitivity (43.8%), gastrointestinal discomfort (30.1%), anorexia (31.5%) | Photosensitivity (5 cases), vomiting, fever, abnormal liver function, dizziness, facial paralysis, hepatocellular tumor (1 case each) |
CAPACITY 2011 | Nausea (36.0%), skin rash (32.0%) | Nausea (36.0%), rash (28.1%), headache (25.9%), cough (25.2%), diarrhea (22.3%) |
Huang 2015 | Skin rash (39.5%), nausea (5.26%), diarrhea (7.89%) | NA |
King 2014 | Nausea (36.0%), rash (28.1%), headache (25.9%), cough (25.2%), diarrhea (22.3%) | Acute exacerbation of IPF, elevated liver enzymes, pneumonia (both 1.1%) |
Lei 2018 | Photosensitivity, loss of appetite, fatigue | NA |
Li 2015 | NA | NA |
Li 2016 | Gastrointestinal reaction, abnormal liver function | NA |
Taniguchi 2010 | Photosensitivity (51.4%), nasopharyngitis (49.5%), anorexia (16.5%) | Photosensitivity (2.8%), lung cancer (1.8%), fever (1.8%), respiratory failure (1.8%) |