| Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | |||||
---|---|---|---|---|---|---|---|---|---|---|
Non-ECMO (n = 986) | ECMO (n = 71) | Non-ECMO (n = 891) | ECMO (n = 67) | Non-ECMO (n = 876) | ECMO (n = 71) | Non-ECMO (n = 798) | ECMO (n = 63) | Non-ECMO (n = 668) | ECMO (n = 58) | |
 PC | 91 (9.2%) | 32 (45.1%) | 91 (10.2%) | 34 (50.7%) | 82 (9.4%) | 36 (50.7%) | 81 (10.1%) | 44 (69.8%) | 74 (11.1%) | 41 (70.7%) |
 VC | 258 (26.2%) | 29 (40.8%) | 238 (26.7%) | 23 (34.3%) | 233 (26.6%) | 24 (33.8%) | 212 (26.6%) | 18 (28.6%) | 189 (28.3%) | 21 (36.2%) |
 PRVC | 366 (37.1%) | 17 (23.9%) | 342 (38.4%) | 17 (25.4%) | 321 (36.6%) | 16 (22.5%) | 289 (36.2%) | 15 (23.8%) | 260 (38.9%) | 13 (22.4%) |
 PS | 1 (0.1%) | 0 | 5 (0.6%) | 0 | 13 (1.5%) | 0 | 16 (2%) | 0 | 22 (3.3%) | 0 |
 Other | 4 (0.4%) | 0 | 8 (0.9%) | 2 (2.9%) | 11 (1.2%) | 2 (2.8%) | 10 (1.2%) | 2 (3.2%) | 9 (1.3%) | 2 (3.4%) |
 PO2 value on ABG (mmHg) | 96.9 (52.7) | 76.2 (36.7) | 90 (35.8) | 79.2 (43.5) | 85.2 (40.7) | 71.9 (29.7) | 82.5 (33.7) | 63.9 (17) | 79.9 (29) | 69.6 (26.2) |
 PCO2 value on ABG (mmHg) | 46 (13) | 47.2 (12.1) | 46 (11.7) | 46.8 (10) | 46.4 (11.9) | 47.1 (11.1) | 48.8 (25) | 49.1 (14.2) | 48.7 (18.6) | 49 (16.3) |
 FiO2 (%) | 82.1 (22) | 80 (23.5) | 62.9 (21.9) | 61.4 (22.8) | 57.2 (20) | 58.1 (22) | 56.3 (24.8) | 59.5 (21.7) | 55.5 (24.8) | 56.9 (18.9) |
 PaO2/FiO2 ratio | 118 | 95.2 | 143.1 | 129 | 149 | 123.7 | 146.5 | 107.4 | 144 | 122.3 |
 Peak pressure (cmH2O) | 31.2 (6.8) | 30 (6.6) | 30.5 (6.4) | 30.4 (8.4) | 29.9 (7.4) | 30.8 (15.9) | 29.5 (7.8) | 28.3 (7.7) | 28.5 (8.2) | 29.5 (5.8) |
 Plateau pressure (cmH2O) | 26.9 (5.8) | 27.2 (6) | 26.9 (6.4) | 25.3 (5) | 26.6 (6) | 28.8 (10.2) | 26.4 (6) | 27.2 (5.1) | 26.1 (5.2) | 27.2 (5.4) |
 PEEP (cmH2O) | 11.3 (3.7) | 10.6 (2.8) | 11.3 (3.1) | 10.2 (2.6) | 11.3 (3.7) | 10.1 (2.5) | 11.3 (7.3) | 10 (2.6) | 10.8 (3.5) | 10.3 (2.2) |
 Tidal volume (ml) | 409.9 (72) | 327.1 (101.7) | 414.9 (66.4) | 307 (108.8) | 412.1 (72) | 325.1 (104.6) | 407.4 (75.3) | 288.8 (127.8) | 409.6 (63.1) | 294.3 (126.6) |
 Respiratory rate (bpm) | 24.3 (5.6) | 19.6 (6.9) | 25.7 (6) | 18.2 (7.2) | 25.6 (6) | 18 (6.7) | 25.9 (6.1) | 18 (6.5) | 26 (6.3) | 19 (13.4) |
 | Day 7 | Day 9 | Day 11 | Day 13 | Day 15 | Day 21 | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Non-ECMO (n = 690) | ECMO (n = 51) | Non-ECMO (n = 630) | ECMO (n = 59) | Non-ECMO (n = 608) | ECMO (n = 64) | Non-ECMO (n = 589) | ECMO (n = 69) | Non-ECMO (n = 551) | ECMO (n = 73) | Non-ECMO (n = 511) | ECMO (n = 60) | |
 PC | 73 (10.6%) | 45 (88.2%) | 58 (9.2%) | 47 (79.7%) | 51 (8.4%) | 44 (68.7%) | 41 (7%) | 33 (47.8%) | 39 (7.1%) | 33 (45.2%) | 27 (5.3%) | 12 (20%) |
 VC | 146 (21.1%) | 15 (29.4%) | 122 (19.3%) | 14 (23.7%) | 92 (15.1%) | 15 (23.4%) | 61 (10.3%) | 16 (23.2%) | 42 (7.6%) | 12 (16.4%) | 23 (4.5%) | 12 (20%) |
 PRVC | 206 (29.8%) | 14 (27.4%) | 170 (26.9%) | 7 (11.9%) | 142 (23.3%) | 4 (6.2%) | 111 (18.8%) | 6 (8.7%) | 68 (12.3%) | 5 (6.8%) | 43 (8.4%) | 7 (11.7%) |
 PS | 33 (4.8%) | 1 (1.9%) | 24 (3.8%) | 1 (1.7%) | 25 (4.1%) | 2 (3.1%) | 14 (2.4%) | 2 (2.9%) | 12 (2.2%) | 1 (1.4%) | 4 (0.8%) | 1 (1.7%) |
 Other | 14 (2%) | 0 | 11 (1.7%) | 0 | 5 (0.8%) | 1 (1.6%) | 8 (1.3%) | 0 | 11 (2%) | 0 | 3 (0.6%) | 3 (5%) |
 PO2 value on ABG (mmHg) | 99.1 (381.2) | 68.5 (15.4) | 81.2 (30) | 69.2 (17.1) | 80.5 (28.1) | 68.4 (16.8) | 81.3 (29.2) | 70.3 (25.1) | 80.4 (25.7) | 68.2 (15.7) | 79.3 (30.5) | 72.1 (25.1) |
 PCO2 value on ABG (mmHg) | 50.6 (31) | 45.8 (10.5) | 48.5 (16.7) | 47.9 (14.3) | 49 (17.4) | 46.2 (13.6) | 50.5 (16.2) | 47.6 (11.2) | 49 (15.8) | 48.5 (13.2) | 51.4 (19) | 49 (15) |
 FiO2 (%) | 55.8 (26.8) | 61.7 (22.2) | 57.5 (22.8) | 60 (23.4) | 59.4 (23.2) | 57.5 (23.5) | 59.1 (24.6) | 58.7 (22.4) | 56.4 (23.3) | 56.7 (21) | 55.1 (22.7) | 60.4 (26.1) |
 PaO2/FiO2 ratio | 177.6 | 111 | 141.2 | 115.3 | 135.5 | 119 | 137.6 | 119.8 | 142.5 | 120.3 | 144 | 119.4 |
 Peak pressure (cmH2O) | 27.9 (8.8) | 30.6 (23.4) | 28.3 (8.6) | 28.4 (6.6) | 28.7 (9.1) | 28.3 (7.2) | 29.1 (9.9) | 29.3 (6.8) | 29.3 (9.6) | 30.3 (6.8) | 28 (6.1) | 26.2 (10) |
 Plateau pressure (cmH2O) | 26 (6.6) | 27.2 (4.7) | 26.1 (6.7) | 25.8 (4.7) | 26.4 (8) | 26.3 (5) | 26.9 (8) | 27.7 (4.5) | 27.6 (6.2) | 27.4 (5.2) | 27.2 (7.7) | 29 (5.1) |
 PEEP (cmH2O) | 10.6 (3.4) | 10 (2.5) | 10.6 (5.3) | 10 (2.4) | 10.1 (3.2) | 9.2 (2.5) | 9.9 (3.2) | 9.8 (2.7) | 10.1 (3.3) | 9.5 (2.3) | 9.6 (3.2) | 8.5 (2.8) |
 Tidal volume (ml) | 408.3 (70.3) | 326.9 (464.2) | 414.6 (68.8) | 266.6 (132.5) | 415.3 (80.8) | 287.8 (132.6) | 410.9 (73.4) | 259.6 (127.4) | 412.9 (91.6) | 280.3 (136) | 404.5 (86.8) | 322.1 (126.4) |
 Respiratory rate (bpm) | 25.7 (6.3) | 18.2 (6.6) | 25.7 (6.5) | 19.5 (9.5) | 25.8 (6.7) | 18.7 (5.7) | 25.9 (7.1) | 19.8 (6.5) | 25.9 (7.3) | 20.2 (6) | 25.2 (6.4) | 30.8 (50.5) |