Table 1 Characteristics of patients in the primary and validation cohorts
From: CT-based radiomic nomogram for predicting the severity of patients with COVID-19
Characteristics | Primary cohort | P value | Validation cohort | P value | ||
|---|---|---|---|---|---|---|
Non-severe group (n = 130) | Severe group (n = 26) | Non-severe group (n = 86) | Severe group (n = 18) | |||
Male | 68 (52.3) | 18 (69.2) | 0.171 | 40 (46.5) | 14 (77.8) | 0.031 |
Age | 42.90 (14.71) | 58.23 (16.23) | < 0.001 | 44.58 (14.37) | 49.50 (13.10) | 0.183 |
Comorbidity | < 0.001 | 0.004 | ||||
0 | 106 (81.5) | 11 (42.3) | 67 (77.9) | 11 (61.1) | ||
1 | 21 (16.2) | 6 (23.1) | 12 (14.0) | 5 (27.8) | ||
2 | 3 (2.3) | 5 (19.2) | 7 (8.1) | 0 (0.0) | ||
3 | 0 (0.0) | 4 (15.4) | 0 (0.0) | 2 (11.1) | ||
Pleural thickening | < 0.001 | < 0.001 | ||||
No | 85 (65.4) | 4 (15.4) | 57 (66.3) | 1 (5.6) | ||
Yes | 45 (34.6) | 22 (84.6) | 29 (33.7) | 17 (94.4) | ||
Pleural effusion | 0.001 | 0.12 | ||||
No | 124 (95.4) | 19 (73.1) | 80 (93.0) | 14 (77.8) | ||
Yes | 6 (4.6) | 7 (26.9) | 6 (7.0) | 4 (22.2) | ||
CRP increase | 0.004 | 0.002 | ||||
No | 63 (48.5) | 4 (15.4) | 41 (47.7) | 1 (5.6) | ||
Yes | 67 (51.5) | 22 (84.6) | 45 (52.3) | 17 (94.4) | ||
WBC abnormal | < 0.001 | < 0.001 | ||||
No | 106 (81.5) | 12 (46.2) | 73 (84.9) | 7 (38.9) | ||
Yes | 24 (18.5) | 14 (53.8) | 13 (15.1) | 11 (61.1) | ||
Lymphocytes abnormal | < 0.001 | 0.006 | ||||
No | 76 (58.5) | 3 (11.5) | 48 (55.8) | 3 (16.7) | ||
Yes | 54 (41.5) | 23 (88.5) | 38 (44.2) | 15 (83.3) | ||
Rad-score | 0.095 (0.018, 0.222) | 0.195 (0.083, 0.337) | < 0.001 | 0.051 (0.012, 0.134) | 0.358 (0.207, 0.653) | < 0.001 |