Table 1 Data of 11 pediatric patients with autoimmune GFAP astrocytopathy
From: Autoimmune glial fibrillary acidic protein astrocytopathy in children: a retrospective study
No. | Gender | Age (month) | Symptoms | Another antibody | CSF abnormality | Main MRI features |
|---|---|---|---|---|---|---|
1 | F | 42 | Fever | Negative | WBC: 341 \(\times\) 106/L glucose: 2.7 mmol/L ADA: 4.48 U/L | Brain: Bilateral juxtacortical WM, cerebellum Meningeal abnormality Sc: normality |
2 | M | 84 | Dizzy Emesis | NMDAR | WBC:50 \(\times\) 106/L glucose: 2.54 mmol/L lactic dehydrogenase: 33.00 IU/L ADA: 4.40 U/L | Brain: Bilateral basal ganglia, thalamus, periventricular WM and callosal Meningeal abnormality Sc: NA |
3 | F | 11 | Mental disorder | Negative | WBC: 120 \(\times\) 106/L | Brain: normality Sc: NA |
4 | M | 67 | Headache Fever | Negative | WBC: 30 \(\times\) 106/L lactic dehydrogenase: 71.00 IU/L ADA:4.5U/L | Brain: NA Sc: NA |
5 | F | 89 | Drowsiness dizzy | Negative | WBC: 240 \(\times\) 106/L glucose: 2.41 mmol/L lactic dehydrogenase: 80.00 IU/L protein: 1.56 g/L | Brain: Bilateral basal ganglia, thalamus, juxtacortical WM and cerebellum Meningeal abnormality Sc: T1-L1 |
6 | F | 52 | Fever Cough | Negative | WBC: 55 \(\times\) 106/L glucose: 2.46 mmol/L lactic dehydrogenase: 39.00 IU/L protein: 0.88 g/L | Brain: Bilateral basal ganglia, thalamus, periventricular WM and pons Sc: normality |
7 | M | 128 | Headache Emesis | Negative | WBC: 550 \(\times\) 106/L glucose: 2.54 mmol/L lactic dehydrogenase: 35.00 IU/L ADA: 5.20 U/L | Brain: pons Sc: NA |
8 | M | 14 | Mental disorder | Negative | normality | Brain: Bilateral periventricular WM Sc: NA |
9 | F | 68 | Drowsiness headache | MOG | WBC: 26 \(\times\) 106/L glucose: 2.42 mmol/L | Brain: Unilateral thalamus, cortical gray, juxtacortical WM, deep gray matter and cerebellum Meningeal abnormality Sc: C2-C7, T8-T12 |
10 | M | 45 | Fever | Negative | WBC: 400 \(\times\) 106/L glucose: 2.74 mmol/L lactic dehydrogenase: 36.00 IU/L protein: 0.63 g/L | Brain: Bilateral thalamus, basal ganglia, juxtacortical WM, periventricular WM, cerebellum T1-weighted “radial enhancing” Meningeal abnormality Sc: normality |
11 | M | 24 | Fever | Negative | WBC: 55 \(\times\) 106/L glucose: 1.83 mmol/L lactic dehydrogenase: 73.00 IU/L | Brain: Bilateral basal ganglia, thalamus, juxtacortical WM, periventricular WM, callosal and pons T1-weighted “radial enhancing” Meningeal abnormality Sc: normality |