Skip to main content

Table 1 Descriptive analysis of adverse events of ivermectin in clinical trials comparing standard (up to 400 µg/kg) vs. high dose (> 400 µg/kg) of ivermectin

From: Repurposing the drug, ivermectin, in COVID-19: toxicological points of view

 

Condition under study

Ivermectin dosage (µg/kg)

Adverse effects rate (%)

Odds ratio or risk difference (95% CI)

Kamgno et al. [70]

Onchocerciasis

0.96 (0.64–1.44)

High dose

800

14.8

Standard dose

150

15

Munoz et al. [33]

Healthy volunteers

0.907 (0.369–2.228)

High dose

401–700

16

Standard dose

200–400

17

Smit et al. [95]

Malaria

6·9% (− 1·9 to 15·7)

High dose

600

11

Standard dose

300

4

Wimmersberger et al. [33]

Trichuriasis

1.346 (0.532–3.405)

High dose

600

27

Standard dose

100–400

22