Table 1 Univariate analysis of postoperative DI
Factors | Non-postoperative DI (n = 130) | Postoperative DI (n = 82) | P value |
|---|---|---|---|
Age (year) | 48 (37, 59) | 51 (40, 63) | 0.540 |
Sex | |||
Wen | 65 (30.7%) | 50 (23.6%) | 0.118 |
Women | 65 (30.7%) | 32 (15.1%) | |
Preoperative cephalocaudal tumor cavity diameter (mm) | 23.0 (18.7, 28.7) | 26.4 (20.9, 33.9) | 0.016 |
Tumor size (cm3) | 4.1 (2.4, 6.6) | 4.9 (2.8, 8.1) | 0.104 |
Tumor size classification | |||
Macroadenoma | 112 (52.8%) | 37 (17.5%) | < 0.001 |
Giant pituitary adenoma | 18 (8.5%) | 45 (21.2%) | |
Pathological tumor type | |||
Gonadotropinoma | 39 (18.4%) | 35 (16.5%) | 0.536 |
Null-cell adenoma | 34 (16.0%) | 20 (9.4%) | |
PRL cell adenoma | 19 (8.9%) | 7 (3.3%) | |
GH cell adenoma | 11 (5.2%) | 4 (1.9%) | |
ACTH cell adenoma | 15 (7.1%) | 8 (3.8%) | |
Plurihormonal | 11 (5.2%) | 7 (3.3%) | |
Thyroid cell adenoma | 1 (0.5%) | 1 (0.5%) | |
Intratumoral cysts or hematoma | |||
Yes | 48 (22.6%) | 40 (18.9%) | 0.088 |
No | 82 (38.7%) | 42 (19.8%) | |
PPBS occurrence | |||
Positive | 116 (54.7%) | 71 (33.5%) | 0.561 |
Negative | 14 (6.6%) | 11 (5.2%) | |
Invasiveness | |||
Yes | 20 (9.4%) | 12 (5.7%) | 0.882 |
No | 110 (51.9%) | 70 (33.0%) | |
The imaginary angle (°) | 91.0 (75.7, 105.3) | 86.0 (68.75, 97.3) | 0.069 |
Postoperative cephalocaudal Tumor cavity diameter (mm) | 15.3 (12.0, 19.1) | 14.6 (10.0, 17.7) | 0.08 |
Change in cephalocaudal tumor cavity diameter after TSS (mm) | 7.17 (2.8, 11.9) | 10.6 (5.9, 17.1) | < 0.001 |
Preoperative pituitary stalk deviation angle (°) | 40.5 (29.5, 51.0) | 45.5 (29.7, 55.0) | 0.061 |
Postoperative pituitary stalk deviation angle (°) | 29.0 (16.5, 40.5) | 29.0 (16.0, 38.5) | 0.612 |
Difference in pituitary stalk deviation angle (°) | 3 (0, 17.2) | 11.5 (0, 22) | 0.003 |
Extent of tumor resection | |||
Total resection | 103 (48.6%) | 70 (33.0%) | 0.515 |
Subtotal resection | 17 (8.0%) | 7 (3.3%) | |
Partial resection | 10 (4.7%) | 5 (2.4%) | |
Intraoperative cerebrospinal fluid leaks | |||
Yes | 22 (10.3%) | 16 (7.5%) | 0.632 |
No | 108 (50.9%) | 66 (31.3%) | |
Length of stay after surgery | 7 (6, 8) | 7 (6, 9) | 0.229 |