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Fig. 1 | European Journal of Medical Research

Fig. 1

From: Inhibitors of IFN gene stimulators (STING) improve intestinal ischemia–reperfusion-induced acute lung injury by activating AMPK signaling

Fig. 1

Experimental schematic diagram. Mice with intestinal ischemia–reperfusion injury (IR) and C-176 treatment. IR: mice received an occlusion of the superior mesenteric artery below the celiac trunk with an arterial microclamp for 60 min and reperfusion for 3 h. C-176: C-176 administered via intraperitoneal injection 30 min before surgical exposure. Compound C: compound C was administered via subcutaneous injection 30 min after the initiation of IR. Vehicle: 10% DMSO and 90% corn oil were administered via intraperitoneal or subcutaneous injection as a control. Sham: mice subjected to identical surgery and vehicle injection except for the occlusion of the superior mesenteric artery

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