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Fig. 6 | European Journal of Medical Research

Fig. 6

From: Inhibitors of IFN gene stimulators (STING) improve intestinal ischemia–reperfusion-induced acute lung injury by activating AMPK signaling

Fig. 6

Compound C reverses the protective effects against ALI in mice exposed to IR. A Total lung water content (TLW). B Content of BALF protein caused by the indicated stimuli 3 h after IR. C Representative photomicrographs of H&E and Masson trichrome-stained sections. Scale bar = 50 μm; arrows indicate lung injury and lung collagen, respectively. D Lung injury score; E the percentage of lung collagen content; F diamine oxidase (DAO) content in serum; and G IL-1β levels in the serum caused by the indicated stimuli 3 h after IR. Data are presented as the mean ± SD (n = 6). IR, C-176, compound C and vehicle are described above. ****P < 0.0001, ***P < 0.001

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European Journal of Medical Research

ISSN: 2047-783X

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