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Table 1 Comparisons of baseline characteristics of patients with T2D with and without MAFLD

From: Atherogenic index of plasma is an independent predictor of metabolic-associated fatty liver disease in patients with type 2 diabetes

 

Non-MAFLD N = 1723

MAFLD N = 824

P-value

Age, years

60.24 ± 10.80

54.70 ± 11.43

 < 0.001

Gender, %(N)

 Female

57% (983)

52.66% (434)

0.022

 Male

43% (741)

47.33% (390)

 

Duration of DM, years

10.87 ± 8.60

9.55 ± 7.35

 < 0.001

SBP, mmHg

133.37 ± 36.24

132.94 ± 76.45

0.877

DBP, mmHg

78.22 ± 9.90

79.49 ± 7.52

0.001

BMI, kg/m2

28.60 ± 5.10

30.65 ± 5.10

 < 0.001

Waist/hip

0.94 ± 0.22

0.94 ± 0.06

0.456

eGFR, mL/min/1.73 m2

79.11 ± 32.15

90.85 ± 36.34

 < 0.001

Microalbuminuria

19.5% (230)

17.1% (92)

0.126

HOMA-IR

3.37 ± 3.03

4.74 ± 3.09

 < 0.001

HDL, mg/dl

45.14 ± 11.90

43.88 ± 11.40

0.010

Non-HDL, mg/dl

135.63 ± 41.57

143.52 ± 43.40

0.003

LDL, mg/dl

95.43 ± 33.69

103.04 ± 34.35

 < 0.001

TG, mg/dl

165.93 ± 93.22

189.03 ± 112.52

 < 0.001

HbA1C, %

8.32 ± 1.752

7.40 ± 1.53

0.031

FBS, mg/dl

160.72 ± 57.31

152.82 ± 51.83

0.001

AST, U/L

19.69 ± 10.95

29.97 ± 18.31

 < 0.001

ALT, U/L

22.36 ± 11.10

42.45 ± 28.07

 < 0.001

ALKP, U/L

150.29 ± 74.89

167.60 ± 90.80

 < 0.001

GGT, U/L

21 (16,33)

30.7 (20,40.25)

0.013

AIP

0.52 ± 0.25

0.59 ± 0.26

 < 0.001

Anti-lipid therapy

 + 

78% (1343)

65.8% (542)

 < 0.001

 −

22% (380)

34.2% (282)

 
  1. MAFLD metabolic-associated fatty liver disease. Age, duration of diabetes mellitus, waist/hip, SBP systolic blood pressure, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, BMI body mass index, HBA1C hemoglobin A1C, HOMA-IR homeostatic model assessment of insulin resistance, HDL high-density lipoprotein, non-HDL, LDL low-density lipoprotein, TG triglyceride, FBS fasting blood glucose, AST aspartate transaminase, ALT alanine transaminase, ALP alkaline phosphatase, AIP atherogenic index of plasma are presented as mean ± standard deviation. Microalbuminuria and gender are presented as percentage (frequency). GGT gamma-glutamyl transferase is presented as median (IQR)