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Fig. 1 | European Journal of Medical Research

Fig. 1

From: A phase Ib dose-escalation study of troriluzole (BHV-4157), an oral glutamatergic signaling modulator, in combination with nivolumab in patients with advanced solid tumors

Fig. 1

Study schema. After registration, participants had a lead-in period of troriluzole monotherapy for 2 weeks to assess tolerance. Nivolumab was added at Week 1 and infusions were every 2 weeks in combination with troriluzole. Tumor assessments were performed by CT scan at baseline, Week 6, Week 12 and every 12 weeks for a year (not shown, schema is truncated for clarity)

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