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Table 5 Correlation analysis of the changes in the multiple parameters with the reduction of ACR at 1 M

From: Correlation between albuminuria and interstitial injury marker reductions associated with SGLT2 inhibitor treatment in diabetic patients with renal dysfunction

 

NRD (eGFR ≥ 60, n = 12)

RD (eGFR < 60, n = 9)

vs %∆ACR

R

p-value

n

R

p-value

n

%∆BMI

− 0.100

n.s

12

0.236

n.s

9

%∆systolic BP

0.354

n.s

12

0.578

n.s

9

%∆diastolic BP

− 0.005

n.s

12

0.578

n.s

9

%∆HbA1c

0.475

n.s

12

0.386

n.s

9

%∆HOMA-R

0.464

n.s

9

− 0.320

n.s

8

%∆Hb

− 0.103

n.s

11

0.087

n.s

8

%∆eGFR

0.299

n.s

12

0.016

n.s

9

%∆NTproBNP

0.474

n.s

10

0.723

n.s

7

%∆FENa

0.194

n.s

11

0.200

n.s

9

%∆NAG/Cr

0.137

n.s

11

0.179

n.s

8

%∆MCP-1/Cr

0.476

n.s

10

0.683

0.042

9

%∆iPF2α-III/Cr

− 0.006

n.s

11

− 0.156

n.s

9

  1. NRD non-renal dysfunction group, RD: renal dysfunction group, R Pearson’s correlation coefficient, BMI body mass index, HOMA-R homeostasis model assessment insulin resistance, ACR urine albumin-to-Cr ratio, NTproBNP N-terminal pro-brain natriuretic peptide, FENa fractional excretion of Na, NAG N-acetyl-β-D-glucosaminidase, MCP-1 monocyte chemotactic protein-1, iPF2α-III 8-iso prostaglandin F2α, n.s. not significant
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European Journal of Medical Research

ISSN: 2047-783X

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