Fig. 4
Effect of furosemide (F) and tadalafil (T) in their conventional, nanoparticle (N) forms and their combinations (o) on the urine osmolarity and specific gravity in rats in adenine (A)-induced chronic renal failure. Data are the means ± SEM (n = 6). ****p < 0.0001 as compared to the adenine group. ap < 0.0001 as compared with the control group. bp < 0.0001 as compared with corresponding nanoparticle group (unpaired t test)