Fig. 5
Effect of furosemide (F) and tadalafil (T) in their conventional, nanoparticle (N) forms and their combinations (o) on the levels of creatinine, urea and total protein in rats serum in adenine (A)-induced chronic renal failure. Data are the means ± SEM (n = 6). ****p < 0.0001, ***p < 0.001, **p < 0.01 and *p < 0.05 as compared to the adenine group. ap < 0.0001 as compared with the control group. bp < 0.05 as compared with corresponding nanoparticle group (unpaired t test)