Fig. 6

Effect of furosemide (F) and tadalafil (T) in their conventional, nanoparticle (N) forms and their combinations (o) on the levels of malondialdehyde, nitrite and reduced glutathione (GSH) in rat’s kidney tissue in adenine (A)-induced chronic renal failure. Data are the means ± SEM (n = 6). ****p < 0.0001, ***p < 0.001, **p < 0.01 and *p < 0.05 as compared to the adenine group. ^ap < 0.01 as compared with the control group. ^bp < 0.01as compared with corresponding nanoparticle group (unpaired t test). ^cp < 0.01 as compared with corresponding nanoparticle group (unpaired t test)