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Fig. 4 | European Journal of Medical Research

Fig. 4

From: CircWDR26 regulates endometrial carcinoma progression via miR-212-3p-mediated typing genes MSH2

Fig. 4

miR-212-3p directly targets TP53 and MSH2 in EC. A Target prediction for miR-212-3p using bioinformatic software Starbase. B Luciferase activity in cells co-transfected with miR-212-3p mimic and WT or MUT TP53, PUM2, MSH2, LDLR, LATS2, and FOXN3. C, D The expression of MSH2 in cells treated with miR-212-3p mimic or miR-212-3p inhibitor was determined by qPCR (C) or western blotting (D). E The expression of p53 MHS2 in normal and EC tissue was measured by qPCR. F The correlation between miR-212-3p and MSH2 expression in EC tissue. *p < 0.05, **p < 0.01, ***p < 0.001

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