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Table 1 Clinical characteristic of patients with sepsis and no sepsis

From: Evidence for the circulating microRNA hsa-let-7d-3p as a potential new biomarker for sepsis in human subjects

Characteristic

All patients (n = 161)

Nonsepsis (n = 66)

Sepsis (n = 95)

p value

Gender (male), n (%)

105(65.2)

37(56.1)

68(71.6)

 < 0.05

Age, (years)

Female

64.0(47.5–78.0)

53.5(43.0–71.25)

67.0(53.0–81.0)

 < 0.05

SOFA score

5.0(3.0–7.5)

3(2–5)

5(4–9)

 < 0.05

APACHEII score

14.0(10.0–20.0)

11.0(9.0–15.0)

16.0(12.0–22.0)

 < 0.05

WBC counts(× 109/L)

10.4(7.4–14.7)

9.2(6.9–12.6)

11.7(7.7–16.8)

 < 0.05

Platelet counts(× 109/L)

150.0(84.3–222.3)

148.0(107.0–220.5)

154.0(78.0–224.0)

NS

CRP (mg/dl)

7.81(3.6–13.1)

4.3(1.0–9.1)

10.8(5.6–15.3)

 < 0.05

Comorbidity conditions, n (%)

 COPD

21(13.0)

10(15.2)

11(11.6)

NS

 Heart failurea

17(10.6)

7(10.6)

10(10.5)

NS

 Coronary heart disease

37(23.0)

14(21.2)

23(24.2)

NS

 Hypertension

59(36.6)

21(31.8)

38(40.0)

NS

 Cerebrovascular disease

24(14.9)

7(10.6)

17(17.9)

NS

 Diabetes mellitus

40(24.8)

17(25.8)

23(24.2)

NS

 Immunosuppression

10(6.2)

1(1.5)

9(9.5)

NS

 Cancer

13(8.1)

8(12.1)

5(5.3)

NS

 Acute pancreatitis

7(4.3)

5(7.6)

2(2.1)

NS

Mortalityb, n (%)

42(26.1)

6(9.1)

36(37.9)

 < 0.00005

  1. SOFA Sequential Organ Failure Assessment; APACHE II Acute Physiology and Chronic Health Evaluation II; NS no significance; COPD chronic obstructive pulmonary disease
  2. aNew York Heart Association class III–IV
  3. bPatients in hospital more than 60 days was considered alive