Fig. 3From: Hydrocephalus: historical analysis and considerations for treatmentProposed mechanism of action of preclinical targets. CSF cerebrospinal fluid, SPAK SPS1-related proline/alanine-rich kinase, TLR4 toll-like receptor 4, TRPV4 transient receptor potential vanilloid 4, NKCC1 sodium potassium 2-chloride cotransporter 1. Figure created in BioRenderBack to article page