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Fig. 2 | European Journal of Medical Research

Fig. 2

From: AMP-activated protein kinase α2 contributes to acute and chronic hyperuricemic nephropathy via renal urate deposition in a mouse model

Fig. 2

AMPK α2 exacerbated kidney injury in a mouse model of chronic HN. a Serum creatinine. b Blood urea nitrogen. c A pathological score of tubular injury in the kidneys. d Quantitative analysis of KIM-1-positive area in the kidneys. e Representative images of PAS staining (arrow: renal tubules dilatation, triangle: brush border shedding, square: tubular vacuolization, round: casts formation) and KIM-1 immunohistochemical staining. f, g Western blot analysis of KIM-1 expression in the kidneys. Each bar represents the mean ± SEM. Versus CON, ***P < 0.001; versus WT, #P < 0.05, ##P < 0.01 and ###P < 0.001

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European Journal of Medical Research

ISSN: 2047-783X

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