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Table 2 Cox regression analysis results of independent prognostic univariate factors for OS in patients with UPS

From: Analysis of prognostic factors of undifferentiated pleomorphic sarcoma and construction and validation of a prediction nomogram based on SEER database

Characteristic

Univariate

  

Wald χ2

P

HR[95%CI]

Age/year

   

 ≤ 73

Ref.

  

 ≥ 74

104.87

 < 0.001

2.80[2.30–3.40]

Sex

   

 Female

Ref.

  

 Male

1.06

0.303

1.11[0.91–1.35]

Race

   

 White

Ref.

  

 Black

3.44

0.064

1.38[0.98–1.95]

 Other

1.01

0.313

0.83[0.58–1.19]

Tumor site

   

 Extremities

Ref.

  

 Trunk

24.50

 < 0.001

1.73[1.39–2.15]

 Head/face/neck

2.37

0.124

1.34[0.92–1.95]

Tumor size/cm

   

 ≤ 5.0

Ref.

  

 5.1–10.0

29.54

 < 0.001

1.98[1.55–2.53]

 10.1–15.0

37.04

 < 0.001

2.53[1.88–3.41]

 ≥ 15.1

48.78

 < 0.001

2.98[2.20–4.06]

Extension

   

 Superficial

Ref.

  

 Deep

34.31

 < 0.001

2.16[1.67–2.80]

 NOS

6.25

0.012

1.53[1.10–2.13]

N stage

   

 N0

Ref.

  

 N1

25.32

 < 0.001

3.28[2.06–5.20]

M stage

   

 M0

Ref.

  

 M1

127.51

 < 0.001

6.25[4.54–8.58]

Grade

   

 I + II

Ref.

  

 III

14.26

 < 0.001

2.05[1.41–2.98]

 IV

14.98

 < 0.001

2.04[1.42–2.92]

Surgery

   

 No/unknown

Ref.

  

 Yes

43.82

 < 0.001

0.29[0.20–0.42]

Radiation

   

No/unknown

Ref.

  

Yes

10.84

0.001

0.72[0.59–0.87]

Chemotherapy

   

No/unknown

Ref.

  

Yes

2.66

0.103

1.22[0.96–1.54]