Table 1 Characteristics of included studies
Descriptions of included studies | Outcomes available for analysis | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
N | Study | Funding | Design | Main criteria | inclusion N | Definition of remission | Definition of response | Induction of Remission wk | Induction of Response wk | |
1 | Chen 2020 | Yes | RCT | CDAI > 220 Anti-TNF naive | 102 | CDA < 150 | ΔCDAI > 70 | ΔCDAI > 100 | 4 | 4 |
2 | Hanauer 2006 | Yes | RCT | CDAI > 220 Anti-TNF naive | 225 | CDA < 150 | ΔCDAI > 70 | ΔCDAI > 100 | 4 | 4 |
3 | Sandborn 2007 | Yes | RCT | CDAI 220–450, IFX resistant | 159 | CDA < 150 | ΔCDAI > 70 | ΔCDAI > 100 | 4 | 4 |
4 | Watanabe 2012 | Yes | RCT | CDAI > 220 | 67 | CDA < 150 | ΔCDAI > 70 | ΔCDAI > 100 | 4 | 4 |