Table 2 Clinical characteristics and outcome in patients with septic shock in the DCS and non-DCS groups
From: Study of damage control strategy for non-traumatic diseases: a single-center observational study
Characteristic | DCS (n = 26) | Non-DCS (n = 31) | P value |
|---|---|---|---|
Age (years) | 76 (47–88) | 79 (57–96) | 0.272 |
Male, n (%) | 14 (53.8) | 18 (58.1) | 0.749 |
Disease | |||
Upper gastrointestinal perforation, n (%) | 1 (3.8) | 7 (22.6) | 0.043 |
Lower digestive tract perforation, n (%) | 12 (46.2) | 17 (54.8) | 0.514 |
Acute intestinal necrosis, n (%) | 9 (34.6) | 3 (9.7) | 0.021 |
Strangulation ileus, n (%) | 3 (11.5) | 1 (3.2) | 0.221 |
Others, n (%) | 1 (3.8) | 3 (9.7) | 0.391 |
Dialysis history, n (%) | 2 (7.7) | 2 (6.5) | 0.855 |
Diabetes history, n (%) | 4 (15.4) | 4 (12.9) | 0.788 |
Taking steroid, n (%) | 3 (11.5) | 1 (3.2) | 0.221 |
Preoperative SOFA score | 7.5 (2–16) | 4 (2–14) | 0.008 |
Respiration | 2 (0–4) | 1 (0–4) | 0.039 |
Coagulation | 1 (0–3) | 0 (0–2) | 0.012 |
Liver | 0 (0–2) | 0 (0–2) | 0.752 |
Cardiovascular | 2 (0–4) | 0 (0–4) | 0.025 |
Central nervous system | 1 (0–4) | 0 (0–4) | 0.027 |
Renal | 1 (0–4) | 1 (0–4) | 0.733 |
Preoperative acute DIC scorea | 3 (1–8) | 2 (0–6) | 0.482 |
Serum lactic acid level just before the end of surgery (mmol/L) | 5.5 (2.3–15.6) | 4.1 (2.2–7.8) | 0.132 |
Operation time (min) | 58.5 (23–158) | 153 (66–289) | < 0.001 |
Bleeding (mL) | 128 (0–2130) | 516 (0–3892) | < 0.001 |
Fluid and blood transfusion volume during surgery (mL) | 3473 (667–7844) | 1928 (851–4582) | < 0.001 |
Use norepinephrine ≥ 0.2 μg/kg/min during surgery, n (%) | 20 (76.9) | 14 (45.2) | 0.015 |
MAP at the start of surgery (mmHg) | 68 (33–107) | 77 (41–136) | 0.143 |
MAP at the end of source control (mmHg) | 65 (51–101) | 63 (42–88) | 0.804 |
OAM complications | |||
No fascia closure, n (%) | 0 (0) | ||
Hemorrhagic complications, n (%) | 0 (0) | ||
Intestinal fistula, n (%) | 0 (0) | ||
Days until closure | 2 (1–9) | ||
28-day mortality, n (%) | 3 (11.5) | 2 (6.5) | 0.499 |
Discharge mortality, n (%) | 6 (23.1) | 5 (16.1) | 0.508 |