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Fig. 2 | European Journal of Medical Research

Fig. 2

From: Effective treatment of intractable diseases using nanoparticles to interfere with vascular supply and angiogenic process

Fig. 2

Intravenously administered anti-miR-21 oligonucleotides formulated with chlorotoxin (CTX)-coupled (targeted) stable nucleic acid–lipid particle (SNALP) innovation accumulates selectively inside of brain tumors as well as facilitate effective miR-21 silencing, resulting in enhanced mRNA and protein levels of its target RhoB, with no evidence of systemic immunogenicity

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