Fig. 4

miR-155-5p targeted SOCS5. A Starbase (http://starbase.sysu.edu.cn/) searched the base binding diagram of miR-155-5p and SOCS5. B Dual luciferase activity assay confirmed SOCS5-WT and SOCS5-MT expressions following miR-155-5p overexpression. C A miR-155-5p overexpression model was engineered in the MLE-12 cell line. qRT-PCR ascertained miR-155-5p expression. D qRT-PCR figured out SOCS5 mRNA expression. E Western blot verified SOCS5 protein expression. NS P > 0.05, ***P < 0.001 (vs. the NC group). N = 3