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Fig. 1 | European Journal of Medical Research

Fig. 1

From: Bile pigments in emergency and critical care medicine

Fig. 1

Bilirubin-biliverdin redox cycle. In the BR-BV redox cycle, BR reductase reduces BV by using NADPH and H + as an electron donor. This forms the products BR and NADP + . When BR is oxidized by ROS, BR reverts to become BV once again. This BV-BR redox cycle demonstrates the potential antioxidative properties of bile pigments in multiple disease models. (BR: bilirubin, BV: biliverdin, ROS: reactive oxygen species)

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European Journal of Medical Research

ISSN: 2047-783X

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