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Table 3 Relationship between S-Klotho pg/ml and hyperuricemia in middle-aged and elderly people

From: Plasma S-Klotho level affects the risk of hyperuricemia in the middle-aged and elderly people

Outcome

Crude model

Model I

Model II

OR (95%CI)

P value

OR (95%CI)

P value

OR (95%CI)

P value

S-Klotho

0.99 (0.98, 1.00)

 < 0.001

0.99 (0.98, 1.00)

 < 0.001

1.00 (0.99, 1.00)

 < 0.001

S-Klotho (quartile)

      

Q1

Reference

 

Reference

 

Reference

 

Q2

0.72 (0.63, 0.80)

 < 0.001

0.74 (0.65, 0.83)

 < 0.001

0.82 (0.72, 0.93)

0.002

Q3

0.62 (0.55, 0.70)

 < 0.001

0.66 (0.58, 0.74)

 < 0.001

0.77 (0.68, 0.88)

 < 0.001

Q4

0.53 (0.47, 0.60)

 < 0.001

0.53 (0.47, 0.61)

 < 0.001

0.67 (0.59, 0.77)

 < 0.001

  1. Model 2: adjusted by age, gender, race
  2. Model 3: with model 2 adjustment variables, as well as variables, such as blood pressure, smoking, BMI, urea, creatinine, triglyceride, high density cholesterol, low density cholesterol, fasting blood glucose, glycosylated hemoglobin, eGFRCKD–EPI, physical activity (PA), heart failure, coronary heart disease, stroke, diabetes. Considering alcohol may influence uric acid metabolism, drinking variable was included in the final model
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European Journal of Medical Research

ISSN: 2047-783X

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