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Table 4 Saturation effect analysis between S-Klotho pg/ml and hyperuricemia using the piecewise logical regression model

From: Plasma S-Klotho level affects the risk of hyperuricemia in the middle-aged and elderly people

Outcome

Crude model

Model II

OR (95%CI)

P value

OR (95%CI)

P value

S-Klotho ≤ 927.8 pg/ml

    

S-Klotho(quartile)

    

Q1

Reference

 

Reference

 

Q2

0.824 (0.717, 0.947)

0.006

0.885 (0.759, 1.032)

0.119

Q3

0.657 (0.569, 0.758)

 < 0.001

0.787 (0.671, 0.922)

0.003

Q4

0.603 (0.521, 0.698)

 < 0.001

0.744 (0.634, 0.874)

 < 0.001

S-Klotho > 927.8 pg/ml

    

S-Klotho(quartile)

    

Q1

Reference

 

Reference

 

Q2

0.964 (0.766, 1.213)

0.754

0.962 (0.746, 1.240)

0.765

Q3

0.798 (0.630, 1.012)

0.063

0.799 (0.614, 1.041)

0.096

Q4

0.838 (0.663, 1.060)

0.143

0.891 (0.683, 1.163)

0.396

  1. Age, gender, race, blood pressure, smoking, drinking, BMI, urea, creatinine, triglyceride, high density cholesterol, low density cholesterol, fasting blood glucose, glycosylated hemoglobin, eGFRCKD–EPI, physical activity (PA), heart failure, coronary heart disease, stroke, diabetes were adjusted