Plasma S-Klotho level affects the risk of hyperuricemia in the middle-aged and elderly people

Table 5 Analysis of the association between S-Klotho pg/ml and hyperuricemia in subgroups

Stratified by gender	Crude model		Model I		Model II
Male
Q1	Reference		Reference		Reference
Q2	0.72 (0.61, 0.85)	< 0.001	0.73 (0.61, 0.86)	< 0.001	0.80 (0.67, 0.95)	0.013
Q3	0.54 (0.45, 0.65)	< 0.001	0.55 (0.46, 0.66)	< 0.001	0.63 (0.52, 0.76)	< 0.001
Q4	0.56 (0.47, 0.67)	< 0.001	0.56 (0.47, 0.67)	< 0.001	0.67 (0.56, 0.81)	< 0.001
Female
Q1	Reference		Reference		Reference
Q2	0.73 (0.62, 0.87)	< 0.001	0.76 (0.64, 0.90)	0.001	0.90 (0.74, 1.09)	0.279
Q3	0.67 (0.57, 0.79)	< 0.001	0.70 (0.59, 0.83)	< 0.001	0.89 (0.73, 1.08)	0.226
Q4	0.51 (0.43, 0.61)	< 0.001	0.52 (0.43, 0.62)	< 0.001	0.72 (0.58, 0.88)	< 0.001
Stratified by Age
*40–65 years*
Q1	Reference		Reference		Reference
Q2	0.77 (0.67, 0.89)	< 0.001	0.79 (0.68, 0.91) 0.0013	0.001	0.87 (0.74, 1.02)	0.081
Q3	0.65 (0.56, 0.76)	< 0.001	0.67 (0.58, 0.77)	< 0.001	0.78 (0.67, 0.92)	< 0.001
Q4	0.57 (0.49, 0.66)	< 0.001	0.56 (0.48, 0.65)	< 0.001	0.69 (0.58, 0.82)	< 0.001
*> 65 years*
Q1	Reference		Reference		Reference
Q2	0.74 (0.60, 0.91)	0.005	0.76 (0.61, 0.94)	0.01	0.84 (0.66, 1.06)	0.145
Q3	0.58 (0.46, 0.72)	< 0.001	0.58 (0.46, 0.72)	< 0.001	0.68 (0.53, 0.87)	0.002
Q4	0.56 (0.45, 0.70)	< 0.001	0.53 (0.43, 0.67)	< 0.001	0.72 (0.56, 0.92)	0.008

ISSN: 2047-783X