Fig. 4

Subgroup analyses of the associations of SUA levels with CVDs in RA patients. BMI body mass index, T2DM, type 2 diabetes mellitus, CKD chronic kidney disease, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TNF tumor necrosis factor, AOR adjusted OR, CI confidence interval. *Normouricemic group was used as the reference in each subgroup analysis. #Adjusted by age, gender (male or female), active smoking (yes or no), BMI, hypertension (yes or no), T2DM (yes or no), TC, TG, LDL-C, HDL-C, serum albumin and CKD (yes or no), disease duration, RF positivity (yes or no), ACPA positivity (yes or no), ESR, CRP, CDAI, HAQ-DI, mTSS and previous treatment, including treatment naïve (yes or no), glucocorticoid (yes or no), methotrexate (yes or no), leflunomide (yes or no), hydroxychloroquine (yes or no), sulfasalazine (yes or no), cyclosporine A (yes or no), TNF inhibitors (yes or no), tocilizumab (yes or no), Janus kinase inhibitors (yes or no), statin (yes or no), aspirin (yes or no). & There was no patient with hypouricemia in CKD group